Pulmonary Embolism Due to Internal Jugular Vein Thrombosis without an Indwelling Catheter

Naganuma, Toru; Dote, Keigo; Kato, Masaya; Sasaki, Shota; Ueda, Kentaro; Kono, Yasuyuki; Watanabe, Yoshikazu; Kajikawa, Masato; Yokoyama, Hiroyuki

doi:10.2169/internalmedicine.48.1551

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…The rate of PE due to secondary UEDVT ranges from 15 to 25%, with an autopsy-proven rate of up to 50% (3). We found several reports on internal jugular vein thrombosis associated with malignancy (lung cancer, prostate cancer, malignant lymphoma, ovarian cancer, and uterine cancer) (5-9). …”

Section: Discussionmentioning

confidence: 91%

Thrombosis in an Internal Jugular Vein and an Upper Limb Deep Vein Treated with Edoxaban

et al. 2017

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A 45-year-old man complained of swelling of the left side of his neck and left upper limb. Ultrasonography and enhanced computed tomography (CT) revealed thrombosis of the left internal jugular, subclavian, and brachiocephalic vein. Based on various examinations, the patient was diagnosed with idiopathic venous thrombosis early in his clinical course. There were no findings to suggest malignancy or abnormal coagulability. However, two months after the start of treatment, the patient was diagnosed with gastric cancer. Despite the presence of Trousseau syndrome, treatment with edoxaban (an oral anticoagulant), reduced the swelling dramatically without any bleeding complications.

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Section: Discussionmentioning

confidence: 91%

Thrombosis in an Internal Jugular Vein and an Upper Limb Deep Vein Treated with Edoxaban

et al. 2017

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“…IJDVT is the most common site of ULDVT, although noncatheter related forms are not well studied and the incidence of PE is not fully known. [41] Notably, IJDVT usually follows intravenous drug abuse, prolonged central venous catheterization, invasive head and neck infections or head and neck trauma. [42] Complications of ULDVT are mortality (10-50%, driven mainly by malignancy), post thrombotic syndrome and DVT recurrence.…”

Section: Discussionmentioning

confidence: 99%

Edoxaban: front-line treatment for brachiocephalic vein thrombosis in primitive mediastinal seminoma: A case report and literature review

Fioretti¹,

Leopizzi²,

Puzzovivo³

et al. 2022

Medicine

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Rationale: Venous thromboembolism is a feared frequent complication of cancer with a 2-way relationship. Low molecular weight heparin is the mainstay of treatment. The use of direct oral anticoagulants is supported by established evidence for the treatment of deep vein thrombosis also in active cancer and they are prioritized over low molecular weight heparin for cancer-associated thrombosis according to current guidelines. However, upper limb deep vein thrombosis is poorly studied with scant data on the use of direct oral anticoagulants in noncatheter-related deep vein thrombosis. We report the case of a patient with noncatheter-related deep vein thrombosis and a rare tumor site effectively and safely treated with a direct oral anticoagulant, edoxaban, after lack of efficacy with low molecular weight heparin. Patient concerns: A 35-year-old man with primitive mediastinal seminoma presented at our Cardio-Oncology Unit for prechemotherapy assessment. Diagnosis: Persistent brachiocephalic deep vein thrombosis, despite full-dose enoxaparin, was detected at ultrasonography. Intervention: We decided to switch the anticoagulant treatment from enoxaparin to edoxaban. Outcome: The 3-month ultrasonography showed almost total regression of the deep vein thrombosis without any adverse effects and a good patient compliance. Lessons: We conducted a literature review on upper limb deep vein thrombosis, since its management is challenging due to inconsistency of evidence. This report highlights the benefits of direct oral anticoagulants compared to low molecular weight heparins in cancer-associated thrombosis therapy in terms of efficacy, safety and ease of use.

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Internal jugular vein thrombosis and pulmonary thromboembolism after head and neck reconstructive surgery

Kitano

Yonezawa

Iwae

et al. 2021

Journal of Plastic, Reconstructive & Aesthetic Surgery

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Pulmonary Embolism Due to Internal Jugular Vein Thrombosis without an Indwelling Catheter

Abstract: Abstract

Cited by 3 publications

References 16 publications

Thrombosis in an Internal Jugular Vein and an Upper Limb Deep Vein Treated with Edoxaban

Thrombosis in an Internal Jugular Vein and an Upper Limb Deep Vein Treated with Edoxaban

Edoxaban: front-line treatment for brachiocephalic vein thrombosis in primitive mediastinal seminoma: A case report and literature review

Internal jugular vein thrombosis and pulmonary thromboembolism after head and neck reconstructive surgery

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