PUlmonary embolism Low incidence in chronic renal failure

Mossey, R. T.

doi:10.1001/archinte.142.9.1646

Cited by 12 publications

(14 citation statements)

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“…All patients were uremic with inhibition of plate let function [10] and pronounced hemodilution. In fact, the incidence of pulmonary em bolism in uremic patients is low [15]. Fur thermore, a postoperative increase in fibrino gen concentration is not seen in these patients [14].…”

Section: Discussionmentioning

confidence: 94%

Deep Vein Thrombosis after Renal Transplantation: A Prospective Analysis of Frequency and Risk Factors

et al. 1985

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In a prospective study the frequency of deep vein thrombosis during the first 3 weeks after kidney transplantation has been evaluated using the combination of thermography and strain-gauge plethysmography for objective diagnosis. 83 consecutive patients were included, 33 with juvenile diabetes mellitus. The overall frequency of thrombosis was 24.1 %, diabetes mellitus being a significant risk factor. No other risk factors were found. The transplant did not influence the venous outflow from the corresponding leg. Plasminogen activator activity in the iliac vein wall at transplantation did not differ between patients with and without thrombosis.

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Section: Discussionmentioning

confidence: 94%

Deep Vein Thrombosis after Renal Transplantation: A Prospective Analysis of Frequency and Risk Factors

et al. 1985

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“…In one large series, Mossey et al reported microscopic or macroscopic PE to be present in 32.3% of patients with normal kidney function, whereas the frequency of PE in patients with stage 5 CKD or ESRD was 9.5%, with all of them being microscopic emboli (41). More recently, Daneschvar et al found no difference in VTE prevalence between autopsied persons with versus without CKD (43).…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Embolism in Patients with CKD and ESRD

Kumar

Sakhuja

Taneja

et al. 2012

Clinical Journal of the American Society of Nephrology

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SummaryBackground and objectives CKD and ESRD are growing burdens. It is unclear whether these conditions affect pulmonary embolism (PE) risk, given that they affect both procoagulant and anticoagulant factors. This study examined the frequency and associated outcomes of PE in CKD and ESRD.Design, setting, participants, & measurements The Healthcare Cost and Utilization Project's Nationwide Inpatient Sample was used to estimate the frequency and outcomes of PE in adults with CKD and ESRD. Hospitalizations for the principal diagnosis of PE and presence of CKD or ESRD were identified using International Classification of Diseases, Ninth Revision codes. Data from the annual US Census and US Renal Data System reports were used to calculate the number of adults with CKD, ESRD, and normal kidney function (NKF) as well as the annual incidence of PE in each group. Logistic regression modeling was used to compare in-hospital mortality among persons admitted for PE who had ESRD or CKD to those without these conditions. ResultsThe annual frequency of PE was 527 per 100,000, 204 per 100,000, and 66 per 100,000 persons with ESRD, CKD, and NKF, respectively. In-hospital mortality was higher for persons with ESRD and CKD (P,0.001) compared with persons with NKF. Median length of stay was longer by 1 day in CKD and 2 days in ESRD than among those with NKF.Conclusions Persons with CKD and ESRD are more likely to have PE than persons with NKF. Once they have PE, they are more likely to die in the hospital.

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“…Autopsy studies suggest that APE-related mortality rates in patients with end-stage renal disease (ESRD) are lower than those in the general population. 29,30 A variety of reasons have been suggested to explain these observations, including platelet dysfunction, bleeding tendency, and anticoagulation therapy during dialysis. In a recent study, Fabbian et al found no relationship between APE-related mortality and CKD or ESRD, 31 yet other studies contradict these findings.…”

Section: Renal Disease and Mortalitymentioning

confidence: 99%