Pulmonary Evaluation in Pediatric Liver Transplant Candidates

Dehghani, Seyed Mohsen; Aleyasin, Soheyla; Honar, Naser; Eshraghian, Ahad; Kashef, Sara; Haghighat, Mahmood; Malek-Hosseini, Seyed Ali

doi:10.1007/s12098-010-0216-9

Cited by 12 publications

(9 citation statements)

References 22 publications

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“…Hepatopulmonary syndrome (HPS) and porto‐pulmonary hypertension (PPHN), both described in more detail below, are potentially life‐threatening conditions that develop as a consequence of portosystemic shunting regardless of the severity of the liver disease . Nonspecific clinical findings include digital clubbing, facial telangiectasia, dyspnea, wheezing, and syncope.…”

Section: Liver Transplant Evaluationmentioning

confidence: 99%

Evaluation of the pediatric patient for liver transplantation: 2014 practice guideline by the american association for the study of liver diseases, american society of transplantation and the north american society for pediatric gastroenterology, hepatolo

et al. 2014

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Section: Liver Transplant Evaluationmentioning

confidence: 99%

Evaluation of the pediatric patient for liver transplantation: 2014 practice guideline by the american association for the study of liver diseases, american society of transplantation and the north american society for pediatric gastroenterology, hepatolo

et al. 2014

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“…HPS and portopulmonary hypertension (PPHN), both described in more detail below, are potentially life-threatening conditions that develop as a consequence of portosystemic shunting regardless of the severity of the liver disease (41,42). Nonspecific clinical findings include digital clubbing, facial telangiectasia, dyspnea, wheezing, and syncope.…”

Section: Cardiopulmonary Assessmentmentioning

confidence: 99%

Evaluation of the Pediatric Patient for Liver Transplantation

Squires

Romero

et al. 2014

J. pediatr. gastroenterol. nutr.

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PREAMBLEC urrent American Association for the Study of Liver Diseases (AASLD) liver transplant evaluation guidelines include both adult and pediatric patients (1). While pediatric liver transplants account for $7.8% of all liver transplants in the United States, sufficient differences between pediatric and adult patients seeking liver transplantation (LT) now require independent, yet complementary documents. This document will focus on pediatric issues at each level of the evaluation process. Disease categories suitable for referral to a pediatric LT program are similar to adults: acute liver failure (ALF), autoimmune, cholestasis, metabolic or genetic, oncologic, vascular, and infectious; however, specific etiologies and outcomes differ widely from adult patients, justifying independent pediatric guidelines. Data supporting our recommendations

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“…lww.com/RHU/A430). The prevalence of digital clubbing in children and adolescents with chronic liver diseases was estimated at 10% 22 and 34.2% 23 (Supplementary Table 6, http://links.lww.com/ RHU/A430).…”

Section: Other Diseasesmentioning

confidence: 99%

Epidemiology of Digital Clubbing and Hypertrophic Osteoarthropathy

et al. 2022

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Digital clubbing and hypertrophic osteoarthropathy (HOA) are long-standing clinical entities, but their prevalence have not been synthesized. We aimed to estimate the prevalence of digital clubbing and HOA in people with existing medical conditions.We comprehensively searched PubMed, Embase, and Web of Science to select studies addressing HOA or digital clubbing and published through March 23, 2021. Summary estimates of the prevalence were derived through random-effects meta-analysis and narrative synthesis. The review protocol has been registered with PROSPERO, CRD42021243934.Of 3973 records, we included 142 studies. In adults, the pooled prevalence of digital clubbing was 33.4% (95% confidence interval [CI], 16.6-52.8), 31.3% (95% CI, 22.4-41.1), 27% (95% CI, 9.4-49.5), and 22.8% (95% CI, 10.8-37.6) in subjects with intestinal diseases, interstitial lung diseases, infective endocarditis, and hepatic diseases, respectively. In children and adolescents, the pooled prevalence of digital clubbing was 29.1% (95% CI, 19.4-39.9), 23% (95% CI, 9.0-41.1), 19.5% (95% CI, 4.1-42.4), and 17.1% (95% CI, 9.5-26.5) in subjects with human immunodeficiency virus infection, hemoglobinopathies, cystic fibrosis, and tuberculosis. The pooled prevalence of HOA was 10.1% (95% CI, 2.0-23.1) in adults with cancers, and 5% (95% CI, 2.5-8.2) in children and adolescents with cystic fibrosis.In conclusion, the prevalence of digital clubbing varied across disease groups in both adults and children. Full-spectrum HOA was mostly reported in adults with liver disease and cancers, and in children and adolescents with cystic fibrosis.

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Pulmonary Evaluation in Pediatric Liver Transplant Candidates

Abstract: Pulmonary evaluation must be performed in all pediatric patients before LT. HPS is not so common among pediatric patients while hypoxemic patients may include a larger proportion of pediatric patients listing for LT.

Cited by 12 publications

References 22 publications

Evaluation of the pediatric patient for liver transplantation: 2014 practice guideline by the american association for the study of liver diseases, american society of transplantation and the north american society for pediatric gastroenterology, hepatolo

Evaluation of the pediatric patient for liver transplantation: 2014 practice guideline by the american association for the study of liver diseases, american society of transplantation and the north american society for pediatric gastroenterology, hepatolo

Evaluation of the Pediatric Patient for Liver Transplantation

Epidemiology of Digital Clubbing and Hypertrophic Osteoarthropathy

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