Pulmonary function and quality of life in patients with morbid obesity six months after bariatric surgery

Xavier, Márcia Arruda Fajardo; Ceneviva, Reginaldo; Filho, José Teixeira; Sankarankutty, Ajith Kumar

doi:10.1590/s0102-86502010000500005

Cited by 21 publications

(11 citation statements)

References 25 publications

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“…Obesity can lead to structural and functional worsening of the cardiovascular and pulmonary system [17, 18], as well as a reduction of the oxidative capacity of skeletal muscles [19]. Cardiopulmonary functional capacity provides diagnostic and prognostic information in a wide variety of clinical settings [20, 21].…”

Section: Introductionmentioning

confidence: 99%

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

Nedeljkovic‐Arsenovic¹,

Banović²,

Radenković³

et al. 2019

Obes Facts

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Background: Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), has become the most frequently used therapy for morbid obesity. Objectives: The aim of this study was to examine the effects of surgically induced weight loss on cardiopulmonary function 6 months after the procedure, as well as the effect of such an intervention on well-known risk factors for cardiovascular diseases. Methods: This is a cross-sectional study on 66 morbidly obese patients (BMI ≥40 or ≥35 kg/m² with present comorbidities), comparing their cardiopulmonary function prior to and 6 months after RYGB surgery. Results: The substantial amount of weight loss (29.80 ± 13.27 kg) after RYGB surgery was associated with significant reduction of comorbidities, especially diabetes and sedentary lifestyle (p = 0.005 and p = 0.002, respectively). Regarding functional capacity, there was significant increase in peak oxygen uptake (VO₂ peak, p = 0.003), duration of exercise testing, metabolic equivalents (exercise time and METs, p < 0.001), and in peak O₂ pulse. These findings were particularly pronounced in a group of patients who had lost more than 18% of initial weight. Conclusions: Reduction of body weight after RYGB surgery is associated with significantly improved cardiorespiratory function 6 months after surgery, especially in patients who lost more than 18% of their initial body weight. In addition, substantial decreases in body weight were also associated with a reduction of cardiovascular risk factors such as diabetes, smoking, hypertriglyceridemia, and sedentary lifestyle.

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Section: Introductionmentioning

confidence: 99%

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

Nedeljkovic‐Arsenovic¹,

Banović²,

Radenković³

et al. 2019

Obes Facts

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“…Severe obesity is associated with both structural and functional impairments to the cardiovascular and pulmonary systems [1,2] and reductions in skeletal muscle oxidative Matthew G. Browning and Robert L. Franco contributed equally to this work. capacity [3].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Cardiopulmonary Responses to Treadmill Walking Following Gastric Bypass Surgery

et al. 2016

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We have demonstrated that weight loss alone was not sufficient to improve select cardiopulmonary fitness measures during treadmill walking in obese females 3 months after GBS. However, we did observe a significant overall improvement in exercise capacity as the GBS group was able to exercise longer, presumably due to significant reductions in body mass and a subsequent reduced metabolic cost of walking.

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“…16,17 In severely obese patients, ventilatory normality is reestablished after weight loss as a consequence of increased FRC, residual volume (RV), total lung capacity (TLC) and ERV. 18,19 In obese people, the presence of adipose tissue around the rib cage and abdomen and in the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The reduction in FRC and in ERV is detectable, even at a modest increase in weight.…”

Section: Introductionmentioning

confidence: 99%

Co - Relation of Six Minute Walk Test With Pulmonary Function Tests in Obese Individuals Admitted for Bariatric Surgery

Bharang¹,

Dosi²,

Tonpay³

2015

jemds

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AIMS AND OBJECTIVES:To evaluate Pulmonary Function Tests and 6MWT in obese individuals and to correlate 6MWT with FEV1 and MMEF 75-25 and establish the individual significance in evaluating bariatric subjects. MATERIAL AND METHOD: Prospective observational study carried out on 50 obese patients referred to PFT Lab for pre-operative investigations (admitted for planned Bariatric Surgery) after the informed consent in Department of Respiratory Medicine, Sri Aurobindo Medical College and Post Graduate Institute, Indore (MP). Biometric data (age, sex, height and weight), Pulmonary Function Tests (PFT) and Six minute walk test (6MWT) data was collected. Exclusion criteria for study is those who were not willing, unable to perform PFT/6MWT acceptably, recent cardiac event, patients with osteoarthritis or neuromuscular disorder and patients with known pre-existing respiratory illness. STATISTICAL ANALYSIS: Statistical analysis was performed using Graphpad Quick Calcs: t test calculator software. The data were reported as mean ± standard deviation (SD). The absolute (6MWD) in meters was used. The correlation between 6MWD and the patient's pulmonary function test were evaluated by applying unpaired 't' test. 6MWT shows extremely significant correlation with FEV1and MMEF 75-25. RESULT: There is high correlation between 6MWT and PFT in obese individuals. All the patients above normal BMI have ventilatory defect which may be due to restriction imposed by abdominal wall and chemical mediators released by adipocytes. Predicted values are calculated by Udwadia Index. CONCLUSION: 6MWT is a good prognostic tool to study ventilatory mechanism in obese individuals. KEYWORDS: PFT, 6MWT, BMI, FEV1, MMEF 75/25. INTRODUCTION:Obesity is a worldwide disease of increasing prevalence, currently representing a major public health problem superimposed on ancient problems such as malnutrition and infectiouscontagious diseases in emerging countries. 1,2 The health consequences of obesity range from a higher risk of premature death to severe chronic diseases that reduce the quality of life. 1 Obesity is a chronic medical condition characterized by an excessive accumulation of fat on human body that causes a generalized increase in body mass. It is measured by using body mass index (BMI) which is a reflection of weight and height. Body mass index (BMI) is calculated as the weight in kilograms divided by the square of the height in meters (BMI = weight (kg) /height (m 2 ). The world Health Organization (WHO) classified obesity using BMI cut-off values of 25 and 30 kg/m 2 Body mass index (BMI) of 18 to 24.9 kg/m 2 is considered normal weight, a BMI of 25.0-29.9 kg/m 2 is considered overweight and a BMI of 30 kg/m 2 or higher is considered obesity. 3 To investigate the effect of obesity on the respiratory system, most researchers use values of pulmonary function tests (PFT). The factors that usually affect the values of pulmonary function tests are age, gender, height, race or ethnic origin and possibly obesity. As the individual gets ...

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Pulmonary function and quality of life in patients with morbid obesity six months after bariatric surgery

Cited by 21 publications

References 25 publications

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

Assessment of Cardiopulmonary Responses to Treadmill Walking Following Gastric Bypass Surgery

Co - Relation of Six Minute Walk Test With Pulmonary Function Tests in Obese Individuals Admitted for Bariatric Surgery

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