Pulmonary function in acute myocardial infarction.

McNicol, Martin W.; Kirby, B. J.; Bhoola, K. D.; Everest, Michelle; Price, Herman L.; Freedman, Sharon F.

doi:10.1136/bmj.2.5473.1270

Cited by 90 publications

(22 citation statements)

References 3 publications

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“…Low PaO,2 values have been associated with an increased incidence of left heart failure, pulmonary edema, hypotension-shock [4,7,12,14,20,21]. Comparing mean PaC02 values in patients with and without complications, Ljungstrom et al [9], H iggs [7], F illmore et al [4], and Sukumalchantra et al [20,21], found no significant differences.…”

Section: Discussionmentioning

confidence: 99%

“…Mean PaCO. was found to be normal [4,7,16], at the lower limit of normal [9,22], or slightly sub normal [14] in patients with AMI, but no significant correlation with the severity of the AMI or other clinical factors was reported. In order to investigate the prognostic value of blood gas analysis blood samples were obtained in more than 400 consecutive cases of AMI initially treated in a CCU.…”

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confidence: 99%

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Arterial Oxygen and Carbon-Dioxide Tension in Patients with Acute Myocardial Infarction

Helmers¹,

Hofvendahl²,

Lundman³

et al. 1973

Cardiology

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Over a 2-year period, 450 cases of acute myocardial infarction were treated in a coronary care unit. Arterial PO₂ and PCO₂, were routinely determined on the day of admission. In this retrospective study, the patients were divided into groups according to their PaO₂ and PaCO₂ and the incidence of various clinical findings. Patients with low PaCO₂ and patients with low PaCO₂ values displayed the highest CCU and hospital mortality. Hypotension-shock and frank pulmonary edema were frequent in these patients. Pulmonary edema also was associated with high PaCO₂ values, but left heart failure without pulmonary edema was only correlated to low PaO₂ values. Supraventricular tachycardia, atrial flutter and fibrillation and left bundle branch block (including hemiblock) were common among patients with low PaO₂ and PaCO₂ values. Ventricular fibrillation was correlated to low PaO₂and high PaCO₂ values. The maximum respiratory rate recorded during the first day after admission proved an important indicator of short-term prognosis.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Arterial Oxygen and Carbon-Dioxide Tension in Patients with Acute Myocardial Infarction

Helmers¹,

Hofvendahl²,

Lundman³

et al. 1973

Cardiology

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“…One patient showed no radiological evidence of left ventricular failure, two patients had minimal changes, five had moderate changes, and two had severe changes. The correlation of the clinical classification with FEV, (1,6,22). An original and more striking finding was the transient development of frequency dependence of RT (Table III, Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Hypoxemia is a common finding in patients after acute myocardial infarction (1)(2)(3)(4)(5)(6). Determination of arterial oxygen pressure (Po2) while patients breathe air or 100% 02, as well as measurements of the physiological dead space, indicate that this hypoxemia results from shunting of blood past unventilated alveoli and uneven distribution of pulmonary ventilation to pulmonary perfusion (7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Interrelation between Alterations in Pulmonary Mechanics and hemodynamics in Acute Myocardial Infarction

Interiano¹,

Hyde²,

Hodges³

et al. 1973

J. Clin. Invest.

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A B S T R A C T Pulmonary mechanics were evaluated in 30 patients with acute myocardial infarction by measuring forced expiratory flow rates and total pulmonary resistance (RT) with the oscillometric method at the resonant frequency of the chest (6-8) cycle/s). During the first 3 days after infarction, forced expiratory volume (FEV) and forced mid-expiratory flow rate (FEF25 75%) were 69% and 60% of predicted values, respectively. 10 or more wk later these values were 95% and 91%. Initially, RT was 52% greater than predicted, but was only 4% greater 10 or more wk later. In 11 patients RT was measured at both resonant frequency and at 3 cycle/s. Five of these patients had no clinical signs of heart failure, but nine had abnormally high values of pulmonary artery pressure, "wedge" pressure and pulmonary extravascular water volume. All of these patients recovered. Initially, RT at resonance was 50% and RT at 3 cycle/s was 130% greater than predicted values. 2-3 wk later these figures were -3% and + 6% of those predicted, respectively. At 10 wk or more, significant frequency dependence of RT had disappeared (RT at 3 cycle/s was 7% greater than RT at resonance). Isoproterenol inhalation in six patients caused no change in flow rates, RT at resonance, or RT at 3 cycle/s. RT

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“…28 These latter 2 studies demonstrated rapid improvements in lung function following treatment for HF as did a study of patients presenting with acute myocardial infarction. 29 Most recently, a multicentre Danish trial examining the effects of nolomirole in HF collected acceptable spirometry data in 527 of its 3,078 subjects. FEV1, FVC and FER was evaluated between 24 and 72 h following admission with the diagnosis of HF at a time when investigators felt subjects no longer had pulmonary congestion.…”

Section: Effects Of Hf On Respiratory Function Testingmentioning

confidence: 99%

Heart Failure and the Lung

Kee

Naughton

2010

Circ J

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Heart failure (HF) is a highly prevalent disease that leads to significant morbidity and mortality. There is increasing evidence that the symptoms of HF are exacerbated by its deleterious effects on lung function. HF appears to cause airway obstruction acutely and leads to impaired gas diffusing capacity and pulmonary hypertension in the longer term. It is postulated that this is the result of recurrent episodes of elevated pulmonary capillary pressure leading to pulmonary oedema and pulmonary capillary stress fracture, which produces lung fibrosis. It is likely that impaired lung function impairs the functional status of HF patients and makes them more prone to central sleep apnoea. (Circ J 2010; 74: 2507 - 2516

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Pulmonary function in acute myocardial infarction.

Cited by 90 publications

References 3 publications

Arterial Oxygen and Carbon-Dioxide Tension in Patients with Acute Myocardial Infarction

Arterial Oxygen and Carbon-Dioxide Tension in Patients with Acute Myocardial Infarction

Interrelation between Alterations in Pulmonary Mechanics and hemodynamics in Acute Myocardial Infarction

Heart Failure and the Lung

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