Pulmonary giant chondromatous hamartoma with multifocal evolution in an infant

Bailly, C; Verschuur, Arnauld; Bosdure, E.; Dabadie, A.; Petit, Philippe; André, Nicolas; Coulomb-L’Herminé, Aurore; Longy, Michel; André, Nicolás

doi:10.1002/pbc.27973

Cited by 2 publications

(2 citation statements)

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“…Hamartoma has an incidence of 0.025% in autopsy series. 6 Furthermore, in the general population, it has been reported to compromise the main stem bronchi in 1.4% of cases. 7 In adults with chronic and intermittent respiratory tract symptoms, a diagnosis of hamartoma must be considered.…”

Section: Introductionmentioning

confidence: 99%

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Severe Central Airway Obstruction Secondary to a Giant Endobronchial Hamartoma: A Case Report

Fernández-Trujillo

Castrillon

Morales

et al. 2023

Journal of Investigative Medicine High Impact Case Reports

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Central airway obstruction refers to the occlusion of more than 50% of the trachea, main stem bronchi, or lobar bronchus. It can potentially become a life-threatening condition. Pulmonary hamartomas (PH) are rare tumors with an incidence of 0.25%, constituting about 8% of all benign lung neoplasms. Only 10% of PH occur endobronchially, while the remaining appear peripherally. We present the case of a women with an endobronchial hamartoma that required emergent resection by bronchoscopy. This is 44-year-old woman, with a history of an endobronchial mass on the right main stem bronchus (RMSB) without histopathological diagnosis or surgical management. She presented with a history of chronic cough and expectoration. Upon admission, a chest X-ray was performed, showing opacities of the right lung and amputations of the RMSB. Bronchoscopy was performed and a tumor-like mass that occludes the RMSB was found, with valve effect causing intermittent occlusion. In anesthetic induction, she presents severe airway obstruction and cardiorespiratory arrest. During resuscitation maneuvers, the lesion that was obstructing the light is seen and resection was performed with electrocautery and cryotherapy probes. Histopathological report described an endobronchial chondromesenchymal hamartoma, with no signs of malignancy. The control X-ray showed adequate re-expansion of the right lung. In conclusion, although endobronchial hamartoma has a low incidence and has a slow growth rate, it can manifest as severe airway obstruction. To achieve a complete resection of an endobronchial lesion, both rigid and/or flexible bronchoscopy plus multimodal interventions are recommended.

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Section: Introductionmentioning

confidence: 99%

“…Hamartoma has an incidence of 0.025% in autopsy series. 6 Furthermore, in the general population, it has been reported to compromise the main stem bronchi in 1.4% of cases. 7…”

Section: Introductionmentioning

confidence: 99%