Pulmonary hamartoma are true neoplasms. Infections are one of the suggested etiologies causing them. But no specific infections have been reported in association with hamartoma. We present the case of a patient with a suspected endobronchial foreign body, who, after an unsuccessful attempt at endoscopic removal, underwent a lobectomy since the lung beyond the obstruction was unsalvageable. The endobronchial lesion proved to be an ossified hamartoma. The destroyed lung was infected with Mycobacaterium tuberculosis. Chronic inflammation caused by tuberculosis could have caused the hamartoma. This combination of endobronchial hamartoma and pulmonary tuberculosis has not been reported in English literature. (Ind J Thorac Cardiovasc Surg 2009; 25: 133-135)