Pulmonary Hemorrhage in Systemic Lupus Erythematosus

Lupus Nephritis Associated with Bacterial Panperitonitis and Lung Alveolar Hemorrhage.

“…Several routes of bacterial invasion, such as via the genital organs and contamination by acupuncture needles in the abdomen which she underwent for her chronic constipation, were possible, but no decisive evidence for these routes was found. Lung alveolar hemorrhage is one of the rare but life threatening complications of SLE (3,4). Some authors have reported that the mortality of the complications is as high as seventy percent (3).…”

“…Lung alveolar hemorrhage is one of the rare but life threatening complications of SLE (3,4). Some authors have reported that the mortality of the complications is as high as seventy percent (3). The cause of this com plication has not been clarified, but some authors have suggested that lupus anticoagulant, vascular fragility due to focal vasculitis and/or presence of antibasement membrane antibody are involved in the development of alveolar hemorrhage (14).…”

“…Some cases show latent morbidity occasionally interrupted by acute intermittent flares, and others have very slowly evolving lesions. Both bacterial panperitonitis and lung alveolar hemorrhage are rare but these are some of the most life threatening complications of SLE (2)(3)(4). The latter in particular has been shown to have a very high mortality rate in several case reports published in the last two decades (3)(4)(5).…”

“…Both bacterial panperitonitis and lung alveolar hemorrhage are rare but these are some of the most life threatening complications of SLE (2)(3)(4). The latter in particular has been shown to have a very high mortality rate in several case reports published in the last two decades (3)(4)(5). Here, we report a patient with lupus nephritis as sociated with panperitonitis and massive pulmonary hemorrhage, who appeared to respond to therapy with methylprednisolone.…”

Pulmonary Manifestations of Systemic Lupus Erythematosus

“…( Badsha et al, 2004;Eagen et al, 1978;Zamora et al, 1997) Its prevalence among SLE patients ranges between <2% and 5.4 % (Santos-Ocampo et al, 2000;Zamora et al, 1997), and the mortality rate ranges between 50% to 90%. ( Erickson et al, 1994;Schwab et al, 1993) Usually it occurs in established disease, especially with lupus nephritis.…”