Pulmonary homograft replacement for primary leiomyosarcoma of the pulmonary artery

Dossche, Karl M.; Wellens, Francis; Jp, Goldstein; Deferm, H.; Bekaert, Y

doi:10.1016/s0022-5223(19)34763-4

Cited by 6 publications

(3 citation statements)

References 4 publications

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“…However, these tumors usually invade the pulmonary trunk, pulmonary valve, or right ventricular outflow tract, necessitating aggressive resection that may include the use of a homograft. 4,5 The second patient described here represents the second report of left atrial wall resection combined with pneumonectomy for a pulmonary vein leiomyosarcoma, and the first report of the resection by thoracotomy through the rib bed. Leiomyosarcoma of pulmonary vein origin is extremely rare; we have found only three cases previously reported worldwide.…”

mentioning

confidence: 87%

Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass

Shimono¹,

Yuasa²,

Yuasa³

et al. 1998

The Journal of Thoracic and Cardiovascular Surgery

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mentioning

confidence: 87%

Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass

Shimono¹,

Yuasa²,

Yuasa³

et al. 1998

The Journal of Thoracic and Cardiovascular Surgery

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“…Radical surgical resection provides the only hope of long-term survival. [1][2][3][4][5] Most primary leiomyosarcomas of the pulmonary trunk are associated with prominent endoluminal growth. The mass in this case, the largest we know of reported to date, was growing into the pericardial space as well as endoluminally, and it had invaded the pulmonary anulus, the interventricular septum, and the free wall of the right ventricular outflow tract.…”

Section: Commentmentioning

confidence: 99%

“…1 Resection lengthens median survival to 10 months, and a few cases of long-term survival have been reported. [1][2][3][4][5] We report a case in which a huge leiomyosarcoma of the pulmonary trunk was radically resected and reconstructed with the aid of cardiopulmonary bypass.…”

mentioning

confidence: 99%

Successful radical resection of a leiomyosarcoma of the pulmonary trunk

Tanaka

Hasegawa

Egi

et al. 2001

The Journal of Thoracic and Cardiovascular Surgery

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Sarcoma of the pulmonary artery: report of four cases with electron microscopic and immunohistochemical examinations, and review of the literature

Johansson

Carlén

1994

Vichows Archiv A Pathol Anat

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Herein we report the clinicopathological features of four cases of pulmonary artery sarcoma that appeared at our institution during a period of 30 years. The patients, 2 males and 2 females, were 50-62 years old. Tumour was found in the pulmonary trunk and right pulmonary artery in all cases, in the pulmonary valve and left pulmonary artery in three of the four cases, and in the right ventricular outflow tract in one case. There was direct extension or metastases to the lungs in two cases, the heart in one case, mediastinum or lymph nodes in two cases and the pleura in one case. Ultrastructural examination in one case revealed cells with features of smooth muscle cells and myofibroblasts. Immunohistochemical examination of three cases gave the following results: vimentin and smooth muscle specific actin was positive in all three cases, desmin in one case and cytokeratin in one case. No positivity was found for Factor VIII. This and other studies indicate that histologically most pulmonary artery sarcomas are leiomyosarcomas or "undifferentiated spindle cell sarcomas". Immunohistochemical and ultrastructural examinations favour an origin from myofibroblasts, probably derived from multipotent (undifferentiated) cells in the wall of the vessel. Most lesions show extensive intrathoracic growth although they rarely metastasize outside the thoracic cavity. They have a poor prognosis although some cases are currently being diagnosed during life.

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Pulmonary homograft replacement for primary leiomyosarcoma of the pulmonary artery

Cited by 6 publications

References 4 publications

Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass

Pulmonary leiomyosarcoma extending into left atrium or pulmonary trunk: complete resection with cardiopulmonary bypass

Successful radical resection of a leiomyosarcoma of the pulmonary trunk

Sarcoma of the pulmonary artery: report of four cases with electron microscopic and immunohistochemical examinations, and review of the literature

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