Pulmonary Hypertension Due to Toxic Oil Syndrome

Gómez-Sánchez, Miguel Ángel; Juan, María José; Gomez-Pajuelo, Casimiro; López, José I.; Atauri, M.J. Díaz de; Martínez‐Tello, Francisco J.

doi:10.1378/chest.95.2.325

Cited by 64 publications

(8 citation statements)

References 19 publications

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“…This was present in all our patients and was often severe [24]. This increase in medial thickness was greater than the one observed in patients with idiopathic pulmonary hypertension with a comparable elevation of pressure [28], a finding previously reported by other authors [21]. This apparent discrepancy could be partly explained from the different aetiology of the pulmonary hypertension.…”

Section: Discussionsupporting

confidence: 45%

Pulmonary vascular remodeling in pulmonary hypertension due to chronic heart failure

Delgado

Conde²,

Sánchez

et al. 2005

European J of Heart Fail

267

164

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Pulmonary hypertension (PHT) associated with chronic heart failure (CHF) is a risk factor of right ventricular failure after heart transplantation (HT). Our aim was to study pulmonary vascular changes in patients with CHF and to assess any correlation with haemodynamic data. Methods: We studied 17 HT recipients with preoperative CHF who died shortly after HT. Preoperative haemodynamic information was obtained immediately before HT. Vascular lesions in muscular arteries were assessed by linear morphometry. Haemodynamic data were correlated with the morphologic changes. Results: Mean transpulmonary gradient (TPG) was 8.9F4.5 mm Hg and pulmonary vascular resistance (PVR) was 2.25F1.34 Wu. According to the threshold for at-risk PHT (TPGN12 mm Hg or PVRN2.5 Wu), six patients had at-risk PHT. Medial thickness was 23.82F7.23% in patients with at-risk PHT and 17.16F3.24% in patients without at-risk PHT ( p=0.018). Conclusions: Medial hypertrophy of muscular pulmonary arteries is more common and severe than expected in patients with CHF, even in patients without at-risk PHT. This structural change could explain why PHT, even in range of values not excluding HT, is a risk factor for right ventricular failure after HT and influences post-HT haemodynamic behaviour.

show abstract

Section: Discussionsupporting

confidence: 45%

Pulmonary vascular remodeling in pulmonary hypertension due to chronic heart failure

Delgado

Conde²,

Sánchez

et al. 2005

European J of Heart Fail

267

164

View full text Add to dashboard Cite

show abstract

“…24 More than 20,000 cases were reported, and many deaths were related to pulmonary hypertension. 24 More than 20,000 cases were reported, and many deaths were related to pulmonary hypertension.…”

Section: Conditions Associated With Pulmonary Vasculopathymentioning

confidence: 99%

Primary Pulmonary Hypertension

Rubin¹

1993

Chest

301

100

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“…27 This increase in medial thickness was greater than that observed in patients with idiopathic PH despite a comparable elevation of pulmonary pressures. 28 In this specific population, intimal fibrosis of pulmonary arteries was not observed; however, the majority of cases had mild PH. 27 Intimal fibrosis is common in the pulmonary vasculature.…”

Section: Reactive or Mixed Phmentioning

confidence: 69%