Pulmonary infiltrates with eosinophilia syndromes in children

Oermann, Christopher M.; Panesar, Kelvin S.; Langston, Claire; Larsen, Gary L.; Menendez, Astryd A.; Schofield, Deborah E.; Cosio, Carmen C.; Fan, Leland L.

doi:10.1067/mpd.2000.103350

Cited by 60 publications

(38 citation statements)

References 18 publications

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“…Accumulation of BAL T-lymphocytes with prevalence of CD4z cells is suggestive of sarcoidosis, whilst prevalence of CD8zcells is suggestive of hypersensitivity pneumonitis [50]. Also, an increase in BAL eosinophils suggests pulmonary infiltrates associated with eosinophilia syndromes [51]. Finally, BAL may help identifying lung involvement in children with nonprimary lung disorders, for example collagen vascular diseases, inflammatory bowel diseases, or liver diseases.…”

Section: Bal Studiesmentioning

confidence: 99%

Task force on chronic interstitial lung disease in immunocompetent children

2004

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Chronic interstitial lung diseases in children represent a heterogeneous group of disorders of both known and unknown causes that share common histological features. Despite many efforts these diseases continue to present clinical management dilemmas, principally because of their rare frequency that limits considerably the possibilities of collecting enough cases for clinical and research studies. Through a Task Force conducted by the European Respiratory Society, which comprised respiratory physicians and basic scientists from across Europe, 185 cases of interstitial lung diseases in immunocompetent children were collected and reviewed. The present report provides important clinically-relevant information on the current approach to diagnosis and management of chronic interstitial lung diseases in children. In addition, recommendations for the management of paediatric interstitial lung diseases, as well as new insights into interstitial lung diseases pathophysiology during childhood are discussed

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Section: Bal Studiesmentioning

confidence: 99%

Task force on chronic interstitial lung disease in immunocompetent children

2004

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“…Eosinophils are rare in healthy children (0-1%) and higher in allergic and parasitic diseases. Pneumocystis carinii infection, interstitial lung disease and drug-induced lung disease also had elevated eosinophil counts in BAL samples (18).…”

Section: Interpretation Of Bal Findingsmentioning

confidence: 99%

The role bronchoscopy in the diagnosis of airway disease in children

Soyer¹

2016

J. Thorac. Dis.

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Bronchoscopy is endoscopic examination of airways that allows both diagnostic and interventional procedures in the evaluation of airway disease in children. It can be performed with either rigid or flexible instruments, depending on the particular needs of patients and skills of bronchoscopist. In addition to visualization of airways, bronchoscopy enables to obtain specimens form lungs and distal airways.Bronchoalveolar lavage (BAL) yields samples from surfaces of the alveoli and aids differential diagnosis of various pulmonary disease. Foreign body removal and examination of anatomy and dynamics of airways are also common indications of bronchoscopy in children. Improvement in the technology, endoscopic instrumentation allows detailed evaluation and interventional manipulation of airway lesions in small children. Although bronchoscopy is considered as a safe procedure, obstruction of airway may challenge and require special endoscopic skills with appropriate instrumentation. This review is aimed to outline the role of bronchoscopy in diagnosis airway disease in children.

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“…Tek taraflı olabileceği gibi sıklıkla iki taraflı ve üst zon yerleşimlidir (4). KEP için tanısal olan pulmoner ödem radyolojik görüntüsünün negatif fotoğ-rafik görüntüsü olguların sadece %25'inde izlenmektedir (5,6). Periferal yerleşimli alveolar lezyonların yanı sıra buzlu cam görünümü en sık gözlenen YRBT bulgularıdır.…”

Section: Discussionunclassified

Chronic Eosinophilic Pneumonia: Two case reports

Cilt¹,

Kurt²,

Erkekol³

et al. 2013

Turk J Bioch

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Kronik Eozinofilik Pnömoni (KEP), etyolojisi bilinmeyen nadir bir interstisyel pnömoni olup, alveol duvarında kalınlaşma ile alveoller ve interstitumun her ikisinde eozinofil ve lenfositlerin infiltrasyonu ile karakterizedir. KEP olan hastalarda bazen astım veya diğer atopik hastalık öyküsü vardır, ama tanı için gerekli değildir. Kortikosteroidler çoğu hasta için ilk basamak tedavidir, ama uygun doz ve tedavi süresi hakkında klavuz önermek için çok az bilgi vardır. Hastalık sıklıkla kortikosteroid tedavisi kesildikten sonra nükseder. Burada, astımla başvuran KEP'li 2 kadın hastanın takibi ilgili literatür ışığında rapor edilmiştir.Chronic Eosinophilic Pneumonia (CEP), a rare idiopathic interstitial pneumonia of unknown etiology, is characterized by infiltration of eosinophils and lymphocytes in both the alveoli and interstitum with a thickening of the alveolar wall. Patients with CEP occasionally have a history of asthma or other atopic diseases, but neither is necessary for the diagnosis. Corticosteroids are the first-line treatment for most patients, but there are little data about the appropriate dose and the duration of therapy to offer guidance. The disease frequently recurs after corticosteroid therapy is discontinued. Herein we report the progress of 2 female patients with CEP manifesting with asthma under the light of the pertinent literature.

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Pulmonary infiltrates with eosinophilia syndromes in children

Cited by 60 publications

References 18 publications

Task force on chronic interstitial lung disease in immunocompetent children

Task force on chronic interstitial lung disease in immunocompetent children

The role bronchoscopy in the diagnosis of airway disease in children

Chronic Eosinophilic Pneumonia: Two case reports

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