Pulmonary Infiltration Due to Aerosol Thesaurosis

Gowdy, John M.; Wagstaff, Mary Jane

doi:10.1080/00039896.1972.10666144

Cited by 33 publications

(4 citation statements)

References 11 publications

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“…In addition, her symptoms recurred and the hypoxemia worsened after several hours' work in the salon. We also found the histol ogy of lung specimens to be consistent with those de scribed in previous reports of lung disease associated with hair spray inhalation [5][6][7]. We excluded other known causes of interstitial pneumonitis and fibrosis, such as idiopathic pulmonary fibrosis, sarcoidosis and hypersen sitivity pneumonitis of known causes.…”

Section: Discussionsupporting

confidence: 69%

Interstitial Pneumonitis and Fibrosis Associated with the Inhalation of Hair Spray

Nagata

Kawajiri²,

Hayashi³

et al. 1997

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We describe a 49-year-old female Japanese hairdresser who presented with a 5-year history of exertional dyspnea, a nonproductive cough, and occasional febrile episodes. Histological analysis revealed interstitial fibrosis with mono-nuclear cell infiltration, foreign body granuloma, and numerous intra-alveolar macrophages and multinucleated giant cells of foreign body type. Arterial blood gas, pulmonary function studies and computed tomographic findings demonstrated improvement 6 months after cessation of exposure to the salon. Bronchoalveolar lavage fluid findings suggested that the development of lung disease in this case was triggered by an allergic mechanism rather than the storage of hair spray ingredients in the lung.

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Section: Discussionsupporting

confidence: 69%

Interstitial Pneumonitis and Fibrosis Associated with the Inhalation of Hair Spray

Nagata

Kawajiri²,

Hayashi³

et al. 1997

Respiration

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“…The results of the present study support the other cross-sectional studies that have found increased prevalence of respiratory symptoms in hairdressers, even after adjusting for smoking. [22][23][24][25] Even asymptomatic workers show prevalence of bronchial obstruction of 4.7%, which denotes the work exposure related upper airway obstruction. Symptomatic workers also show 28% bronchial obstruction.…”

Section: Discussionmentioning

confidence: 99%

A study of the prevalence of respiratory morbidity and ventilatory obstruction in beauty parlour workers

Kesavachandran

Rastogi

Mathur

et al. 2006

Indian J Occup Environ Med

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“…In the latter view, deformation of MEFV curves reflects alteration in periph eral airways caliber, phase III slope devia tions represent abnormalities in the elastic properties of the air spaces, and a rise in closing volume can result from both periph eral airway disease and loss of elasticity. Use of single-breath nitrogen and MEFV curves obtained in concert has been infor mative in longitudinal studies of the effects on pulmonary target areas of subjects ex posed to direct [39] and indirect [4] inhal ants, and may detect changes from environ mental pollutants over and above cigarette effects [34], There have been no similar prospective studies of the pulmonary re sponses of healthy subjects to hair-grooming aerosols, the relationship between their use and lung abnormalities resting on the in ferences of animal studies [20], radiologic correlations [25] and occupational investi gations [33,37]. With the exception of the notable Zuskin and Bouhuys contribution [40], the few respiratory function analyses of nonoccupational effects of hair-sprays used the less sensitive spirometric methods [18, 281. Our results in the initial phase of a pro spective study do not confirm the ability of the hair-spray aerosol used to induce acute changes in the small airways of healthy subjects, even with exposures exceeding the manufacturer's instructions for 'heavy' ap plication.…”

Section: Discussionmentioning

confidence: 99%

Peripheral Airway Responses to Acute Hair-Spray Exposure

Cohen¹

1977

Respiration

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The acute phase of a longitudinal study of pulmonary function responses to a hair-grooming aerosol included determinations of lung and forced expiratory volumes, derivatives of maximal expiratory flow-volume (MEFV) curves, closing volume information and the slope of the alveolar plateau (phase III) before and 1, 3 and 5 min after a 20-sec application of the spray to 30 healthy subjects. Baseline indices approximated individual prediction standards except for an increased mean slope of the alveolar plateau. After exposure there were meaningful changes in forced vital capacity, forced expiratory volume for the first second and the ratio of residual volume to total lung capacity suggestive of a modest bronchodilatation. Closing capacity decreased significantly without changes in the means for CV and the phase III slope. Flow rates at low lung volumes were unaltered except for a significant rise in V_max50%. Although their control means were alike for all physiologic indices, a post-aerosol decrease in a single flow rate (FEF_75%) and a further increase in the phase III slope appeared to differentiate the responses of the 17 smokers from those of the 13 nonsmokers. This single hair-spray exposure did not induce mean changes in terminal flow rates or measurable effects on other ‘early tests’ for the entire group indicative of peripheral airway constriction. The same subjects are having serial determinations made during 1 year of daily use of the same product.

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Pulmonary Infiltration Due to Aerosol Thesaurosis

Cited by 33 publications

References 11 publications

Interstitial Pneumonitis and Fibrosis Associated with the Inhalation of Hair Spray

Interstitial Pneumonitis and Fibrosis Associated with the Inhalation of Hair Spray

A study of the prevalence of respiratory morbidity and ventilatory obstruction in beauty parlour workers

Peripheral Airway Responses to Acute Hair-Spray Exposure

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