Pulmonary intravascular lymphoma diagnosed by 18-fluorodeoxyglucose positron emission tomography-guided transbronchial lung biopsy in a man with long-term survival: a case report

Abstract

Introduction18-Fluorodeoxyglucose positron emission tomography can detect the pulmonary involvement of intravascular lymphoma that presents no abnormality in a computed tomography scan.Case presentationWe report the case of a 61-year-old Japanese man who had pulmonary intravascular lymphoma and no computed tomography abnormality. We were able to make an antemortem diagnosis of pulmonary intravascular lymphoma by transbronchial lung biopsy according to 18-fluorodeoxyglucose positron emission tomography findings. He is free of recurrent disease 24 months after chemotherapy.ConclusionsTo the best of our knowledge, this is the first reported case of a long-term survivor of pulmonary intravascular lymphoma diagnosed by transbronchial lung biopsy under the guide of 18-fluorodeoxyglucose positron emission tomography.

FDG-PET/CT is a pivotal imaging modality to diagnose rare intravascular large B-cell lymphoma: case report and review of literature

“…In this setting, several authors have reported that FDG‐PET could be useful for the diagnosis of IVLBCL when this type of lymphoma is clinically suspected . The potential interests of FDG‐PET/CT in IVLBCL reported in literature are summarized in Table .…”

“…When diagnosed early, it is, however, potentially treatable [2,11]. In this setting, several authors have reported that FDG-PET could be useful for the diagnosis of IVLBCL when this type of lymphoma is clinically suspected [3,4,[7][8][9][10][12][13][14][15][16][17][18][19][20][21][22]. The potential interests of FDG-PET/CT in IVLBCL reported in literature are summarized in Table 1.…”

Indication for Random Skin Biopsy for the Diagnosis of Intravascular Large B Cell Lymphoma

“…In earlier reports, IVLBCL was diagnosed by biopsy of involved organs including the lung, lacrimal gland and prostate [9,10,11]. In 81 IVLBCL cases reported by Murase et al [12] the diagnostic sites were the bone marrow (54), liver (14), spleen (6), lung (5) and the adrenal gland, brain and kidney (2).…”

PET Molecular Imaging–Directed Biopsy: A Review

“…FDG PET has been considered a “metabolic biopsy” [39] tool in the evaluation of nonlung lesions with indeterminate biopsy results. Niida et al [40] reported a case in which pulmonary intravascular lymphoma was diagnosed with FDG PET–guided transbronchial lung biopsy. Purandare et al [28] found that lung biopsies were performed only after the needle tip was confirmed to be in the portion of the lesion corresponding to the hypermetabolic area seen on PET images.…”