Pulmonary manifestations of leptospirosis

Gulati, Shilpa; Gulati, Anu

doi:10.4103/0970-2113.102822

Cited by 60 publications

(56 citation statements)

References 56 publications

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“…49 Severe forms of the disease with multiorgan dysfunction and ARDS-like syndromes may be fatal. 50 Chest roentgenogram findings are non-specific; they commonly show non-segmental patchy or even nodular infiltrates with poorly defined margins usually in the lower lobes, which can be unilateral or bilateral. 51 Interestingly, leptospirosis and chikungunya coinfection can potentially lead to a delayed diagnosis and subsequent deleterious outcomes.…”

Section: Leptospirosismentioning

confidence: 99%

Pneumonia in the tropics

Lim

Siow

2017

Respirology

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Pneumonia in the tropics poses a heavy disease burden. The complex interplay of climate change, human migration influences and socio-economic factors lead to changing patterns of respiratory infections in tropical climate but also increasingly in temperate countries. Tropical and poorer countries, especially South East Asia, also bear the brunt of the global tuberculosis (TB) pandemic, accounting for almost one-third of the burden. But, as human migration patterns evolve, we expect to see more TB cases in higher income as well as temperate countries, and rise in infections like scrub typhus from ecotourism activities. Fuelled by the ease of air travel, novel zoonotic infections originating from the tropics have led to global respiratory pandemics. As such, clinicians worldwide should be aware of these new conditions as well as classical tropical bacterial pneumonias such as melioidosis. Rarer entities such as co-infections of leptospirosis and chikungunya or dengue will need careful consideration as well. In this review, we highlight aetiologies of pneumonia seen more commonly in the tropics compared with temperate regions, their disease burden, variable clinical presentations as well as impact on healthcare delivery.

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Section: Leptospirosismentioning

confidence: 99%

Pneumonia in the tropics

Lim

Siow

2017

Respirology

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“…There was consolidation in the dorsal segment of the left lung in Patient 5, and he required intubation. Gulati et al reported pulmonary involvement in 20-70 of patients in the immune phase with pulmonary radiographic alterations varying from 11 to 67 (11), and GGO revealed by CT was due to airspace hemorrhage. All patients in this study survived without residual symptoms, and the mean length of hospitalization was 38.0 days ( 17.0 days).…”

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confidence: 99%

Leptospirosis Cases in the Tokyo Metropolitan Area, Japan

et al. 2017

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“…Highresolution CT (HRCT) typically shows ground-glass appearance with consolidation and nodules in the air spaces. 7,8 The diagnosis of leptospirosis can be made by serological tests which involve detection of antibodies, bacterial culture from appropriate specimen sampling, antibody-labelled fluorescent markers, polymerase chain reaction (PCR) and immunostaining. 1 The patient was a farmer and in all probability acquired the disease through his occupation and contact with field animals.…”

Section: Discussionmentioning

confidence: 99%

A Case of Pulmonary Haemorrhage and Acute Kidney Injury 2C01

Bartakke

Muench

2014

Journal of the Intensive Care Society

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Leptospirosis is a zoonotic bacterial infection with a reservoir in rodents and farm animals. It is a common disease in tropical countries but rare in the UK. The severe form (Weil's disease) caused by Leptospira is potentially fatal and includes liver failure, renal failure and haemorrhagic pneumonitis. Typical early symptoms of leptospirosis such as myalgia, headache, conjunctivitis and fever may be absent. Careful history-taking for contact with rodents or their excrement and/or farm animals should be performed to identify patients at risk for leptospirosis. Patients with pulmonary haemorrhage and kidney failure should be screened for leptospirosis. Liver failure may be attenuated or delayed by weeks. We describe a case which proved difficult to diagnose.

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Pulmonary manifestations of leptospirosis

Cited by 60 publications

References 56 publications

Pneumonia in the tropics

Pneumonia in the tropics

Leptospirosis Cases in the Tokyo Metropolitan Area, Japan

A Case of Pulmonary Haemorrhage and Acute Kidney Injury 2C01

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