Pulmonary mechanics during isoflurane, sevoflurane and desflurane anaesthesia

Dikmen, Yalım; Eminoglu, E; Salihoğlu, Ziya; Demiroluk, Sener

doi:10.1046/j.1365-2044.2003.03285.x

Cited by 94 publications

(60 citation statements)

References 11 publications

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“…With exception of desflurane, which at high alveolar concentrations has been shown to increase airway resistance, volatile anesthetic agents produce reliable bronchodilatation [5]. Cases of rhabdomyolysis and intraoperative cardiac arrest secondary to hyperkalemia during the use of inhaled anesthetics in patients with DMD are described [6,7].…”

Section: Discussionmentioning

confidence: 99%

Duchenne Muscular Dystrophy: Management of Difficult Airway and Concurrent Bronchospasm

Chiu¹,

Patel²,

Tilak³

2012

J Anesthe Clinic Res

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Using succinylcholine and inhalation agents for patients with Duchenne muscular dystrophy is extremely risky. Those risks include heart failure, cardiac dysrhythmias, rhabdomyolysis and malignant hyperthermia. Even in emergent situations, such as intraoperative bronchospasm, succinylcholine and inhalational agents are often considered contraindicated. Nevertheless, if intraoperative bronchospasm does occur in a patient with Duchenne muscular dystrophy, the benefits of using inhalational agents to treat bronchospasm may outweigh the risks in certain situations.

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Section: Discussionmentioning

confidence: 99%

Duchenne Muscular Dystrophy: Management of Difficult Airway and Concurrent Bronchospasm

Chiu¹,

Patel²,

Tilak³

2012

J Anesthe Clinic Res

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“…The pharmacodynamics of desflurane are similar to those of isoflurane. That volatile anesthetics affect the respiratory system has been well documented in previous studies (2)(3)(4); for example, they reduce the ciliary beat frequency (CBF) in vitro (5,6) and increase the permeability of the alveolar-capillary barrier (7,8).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the effects of desflurane and sevoflurane anesthesia on alveolar epithelial permeability by Tc-99m DTPA inhalation scintigraphy

Iskender¹,

Erkan²,

Erbaş³

et al. 2013

Turk J Med Sci

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Eight new mono-azo substituted chromogenic calix [4]arenes (1-8) were synthesized by diazo-coupling reactions in which 25,26,27-tribenzoyloxy-28-hydroxy-5,11,17-tri-(tert -butyl)calix[4]arene and diazonium salts (2-, 3-, and 4-nitroaniline; 4-phenyl azoaniline; 3-and 4-chloroaniline; or 2-and 4-methylaniline) formed the corresponding mono-azo substituted derivatives in high yields. The mono-azo substituted calix[4]arenes were characterized by UV-Vis, FT-IR, and 1 H-NMR spectroscopic techniques. Elemental analysis was also carried out. In addition, the effects of varying pH levels and solvents upon the absorption ability of azocalix[4]arenes substituted with electron-donating and electron-withdrawing groups at their o -, m -, and ppositions were studied. The results proved that the absorption maxima of the prepared compounds showed large bathochromic effects in comparison with analog compounds containing aromatic amine residue. Furthermore, concentration effects on the visible absorption maxima of the azocalix[4]arene compounds studied were also reported.

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“…Sevoflurane has emerged as the volatile agent of choice, as studies indicate it has the most pronounced bronchodilatory effect of all volatile anesthetics [60]. Desflurane increases airway resistance [61][62][63] and should be avoided in asthmatics, specifically at lighter levels of general anesthesia.…”

Section: Intraoperative Managementmentioning

confidence: 99%

The Perioperative Management of Asthma

Applegate

2013

J Allergy Ther

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Anesthesiologists encounter asthmatic patients routinely. This common disease frequently complicates the perioperative care of those patients who live with it and can occasionally lead to life-threatening complications. This review takes the anesthesiologist's perspective to discuss asthma and how asthmatic patients can be safely guided through an anesthetic. We will discuss frequently used asthma medications, pre-operative disease optimization, management of intra-operative bronchospasm, and post-operative considerations for asthmatic patients. Anesthesiologists can make a positive difference in the outcomes of these patients with proper preoperative evaluation using a stepwise approach to disease management and by minimizing bronchoconstriction and effectively treating it when it develops.

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Pulmonary mechanics during isoflurane, sevoflurane and desflurane anaesthesia

Cited by 94 publications

References 11 publications

Duchenne Muscular Dystrophy: Management of Difficult Airway and Concurrent Bronchospasm

Duchenne Muscular Dystrophy: Management of Difficult Airway and Concurrent Bronchospasm

Evaluation of the effects of desflurane and sevoflurane anesthesia on alveolar epithelial permeability by Tc-99m DTPA inhalation scintigraphy

The Perioperative Management of Asthma

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