Pulmonary metastasis from renal synovial sarcoma treated by stereotactic body radiotherapy: A case report and review of the literature

Abstract

Primary synovial sarcoma of kidney is an uncommon neoplasm, metastasizing most commonly to lung. Surgery and/or palliative chemotherapy for pulmonary metastases is commonly used to improve tumor control and survival. Stereotactic body radiotherapy (SBRT) is a relatively new approach to treat pulmonary metastasis, encouraged by the results of cranial and spinal stereotactic radiosurgery. The local control and toxicity profile of patients with pulmonary metastasis treated with SBRT are comparable to pulmonary metastatectomy. Furthermore, with advancement of imaging techniques, immobilization techniques, tumor-tracking techniques, and treatment planning and delivery system, SBRT can now be alternatively employed for the treatment of pulmonary metastasis as a comparable substitute to surgical resection.

SS18-SSX Expression in a Contemporary Cohort of Primary Renal Synovial Sarcoma: A Multi-Institutional Experience of Fourteen Patients

“…Tumors reported in the literature ranged in age from 4 to 76 years with a median of 36.2 years. [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] In published cases, 3% of patients were younger than 18 years of age which is less than in our cohort. There is a slight male predominance both in published cases (M: F = 1.14:1) and in our cohort (1.8:1).…”

“…5,6 Primary renal synovial sarcoma is one of the rarest types of sarcomas of kidney and comprises 2% of all malignant renal tumors and 1% of all synovial sarcomas across the anatomic sites. 7 The first case of primary renal synovial sarcoma was reported by Argani et al in 2000 and to date, 88 case reports and 23 case series, [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] with only two case series consisting of more than 14 tumors, have been reported in the literature. 8,9 The most common presenting symptoms include hematuria, pain, and palpable mass.…”

Synovial Cell Sarcoma of the Kidney: A Case Report

“…Primary renal sarcomas are rare neoplasm that account about 1% of malignant renal tumors [3]. Prevelance of primary renal Synovial cell sarcoma is rare and comprise 1-3% of all malignant renal neoplasm [4]. The first case of primary renal Synovial cell sarcoma was reported in 1999 and at 2000, Argani et al, published another case of renal SCS [5].…”

Primary Synovial Sarcoma of Kidney: A Rare Differential Diagnosis of Renomegaly

“…Rough male to female ratio is 1.7 : 1 [ 2 ]. Prevalence of primary renal SS is rare and comprises 1–3% of all malignant renal neoplasms [ 8 ]. The first case was reported in 1999 and Argani et al published the first case of renal SS in 2000 [ 9 ].…”