Pulmonary nocardiosis in a patient treated with corticosteroid therapy

Narushima, Mitsunaga; Suzuki, Hajime; Kasai, Tomihiko; Tsuzura, Yutaka; Tomita, Shunsuke; Endoh, Shigeru; Yamada, Masaya; Ohtsuka, H

doi:10.1046/j.1440-1843.2002.00370.x

Cited by 13 publications

(6 citation statements)

References 5 publications

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“…We considered its use for refractory cases of actinomycetomas on the basis of earlier in vitro and in vivo studies. Imipenem has demonstrated good in vitro activity against various strains of Nocardia 18 and A madurae, 19 and has been successfully used to manage cerebral and pulmonary nocardiosis, [20][21][22][23] and nonmycetoma cutaneous infection with Nocardia. 24 In addition, case reports have described the efficacy of imipenem and amikacin combination therapy for S somaliensis and N veterana actinomycetomas.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of imipenem therapy for Nocardia actinomycetomas refractory to sulfonamides

Ameen¹,

Arenas²,

Mercado³

et al. 2010

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

Efficacy of imipenem therapy for Nocardia actinomycetomas refractory to sulfonamides

Ameen¹,

Arenas²,

Mercado³

et al. 2010

Journal of the American Academy of Dermatology

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“…Risk factors for Nocardia infection include long-term corticosteroid exposure, malignancy, HIV infection, and a history of solid organ transplantation. [3–11]…”

Section: Introductionmentioning

confidence: 99%

Nocardiosis in a tertiary care hospital in Saudi Arabia

Al-Jahdali

Baharoon

Alothman

et al. 2011

J Global Infect Dis

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Background:Nocardiosis is an uncommon bacterial infection that is caused by aerobic actinomycetes of the genus Nocardia. This pathogen has emerged as an important cause of mortality and morbidity among both immunocompetent and (more commonly) immunocompromised hosts. The prevalence of nocardiosis is unknown in Saudi Arabia. Only sporadic cases of cutaneous nocardiosis have been reported. In this study, we performed a 10-year retrospective review of all cases of nocardiosis identified at the King Fahad National Guard Hospital in Riyadh. Clinical presentation, risk factors, site of disease involvement, radiological features, and outcomes of 30 patients with pulmonary and disseminated nocardiosis are presented.Materials and Methods:A retrospective chart review of all cases of nocardiosis over the last ten years.Results:Thirty cases of nocardiosis were identified. The disease was more common in males. Fever and cough was the most common presentation. Most of the patients had an underlying pulmonary disease. Consolidation was the most prevalent radiological feature. Pleural effusion was common. Unfortunately, none of the isolates were sub-speciated. Cure was possible in 40% of the cases. Ten percent of patients died, while follow-up on the rest of the patients was lost.Conclusion:Nocardiosis is not uncommon in Saudi Arabia. Cases are not restricted to the classical immunocompromised host. A database is urgently needed to better evaluate the prevalence of the illness among the Saudi population.

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“…Foram relatados casos de pacientes em tratamento com corticóide ou quimioterapia imunossupressora 1 2 9 10 14 16 18 .Comumente se apresenta como doença subaguda ou crônica, podendo mimetizar tuberculose, abscesso ou câncer de pulmão 16 . Em humanos o complexo Nocardia asteróides é o patógeno predominante 5 15 .…”

Section: Discussionunclassified

Nocardiose pulmonar em paciente usuário crônico de corticóides

Brasileiro

Pinho

Medeiros

et al. 2007

Rev. Soc. Bras. Med. Trop.

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RESUMO Nocardiose pulmonar é uma infecção grave e incomum causada pela RELATO DE CASOPaciente do sexo masculino, 49 anos, apresentou-se com queixa de mal estar geral, perda de apetite, tosse seca, dor para deglutir e febre alta a três semanas da admissão. Era acompanhado no serviço de clinica médica do Hospital Heliópolis com diagnóstico de púrpura trombocitopênica idiopática há quatro anos e esplenectomizado há quatro meses. Quando procurou este serviço, estava em uso de prednisona 1mg/kg/dia. Ex-tabagista, 45 anos/maço.Ao exame físico apresentava-se em bom estado geral, levemente hipocorado, fascies cushingóide, temperatura axilar de 38°C, freqüência cardíaca de 90bpm, pressão arterial de 130/80mmHg e freqüência respiratória de 20rpm. Cavidade oral com placas esbranquiçadas removíveis, lesão herpetiforme em língua. À palpação cervical, apresentava nódulo tireoidiano sólido e indolor de aproximadamente dois centímetros. Aparelho respiratório com estertores crepitantes difusos bilaterais e ausculta cardíaca sem alterações.Seus exames laboratoriais evidenciaram hemoglobina de 10,9g/dl, leucócitos de 23.100mm 3 com 7% bastões e

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Pulmonary nocardiosis in a patient treated with corticosteroid therapy

Cited by 13 publications

References 5 publications

Efficacy of imipenem therapy for Nocardia actinomycetomas refractory to sulfonamides

Efficacy of imipenem therapy for Nocardia actinomycetomas refractory to sulfonamides

Nocardiosis in a tertiary care hospital in Saudi Arabia

Nocardiose pulmonar em paciente usuário crônico de corticóides

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