Pulmonary Rehabilitation in Advanced Lung Cancer Patients During Chemotherapy

Jastrzębski, Dariusz; Maksymiak, M.; Kostorz, Sabina; Bezubka, B.; Osmanska, I.; Młyńczak, Tomasz; Rutkowska, Anna; Baczek, Z.; Ziora, Dariusz; Kozielski, Jerzy

doi:10.1007/5584_2015_134

Cited by 50 publications

(51 citation statements)

References 14 publications

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“…Recently, several trials have reported positive results with supervised PA interventions. 23 - 25 To be sure, supervised PA interventions are able to implement more intense PA in a safe setting. However, the frequency of PA sessions is limited, travel burden is placed on the patient, and increases in activity outside the activity sessions are not assured.…”

Section: Discussionmentioning

confidence: 99%

A Patient-Centered Activity Regimen Improves Participation in Physical Activity Interventions in Advanced-Stage Lung Cancer

et al. 2018

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Introduction: Physical activity (PA) is a potential therapy to improve quality of life in patients with advanced-stage lung cancer (LC), but no PA regimen has been shown to be beneficial, clinically practical, and sustainable. We sought to test the hypothesis that a patient-centered activity regimen (PCAR) will improve patient participation and PA more effectively than weekly phone calls. Methods: In patients with advanced-stage LC, we implemented a walking-based activity regimen and motivated patients via either weekly phone calls (n = 29; FitBit Zip accelerometer) or PCAR (n = 15; FitBit Flex, an educational session, and twice-daily gain-framed text messages). Data collection over a 4-week period was compared, and a repeated-measures, mixed-effects model for activity level was constructed. Results: Subjects receiving PCAR more frequently used the device (100% vs 79%) and less frequently had missing data (11% vs 38%). “More active” and “less active” groups were created based on mean step count in the first week. “Less active” patients in the PCAR group increased their PA level, whereas PA level fell in the “more active” group. Most subjects found PCAR helpful (92%) and would participate in another activity study (85%). Discussion: Compared with weekly phone calls, PCAR has higher patient participation, is more likely to improve PA in “less active” subjects, and has high patient satisfaction. A multifaceted PA regimen may be a more efficacious mechanism to study PA in advanced LC. PCAR should be used in a randomized controlled trial to evaluate for improvements in symptom burden, quality of life, and mood.

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Section: Discussionmentioning

confidence: 99%

A Patient-Centered Activity Regimen Improves Participation in Physical Activity Interventions in Advanced-Stage Lung Cancer

et al. 2018

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“…Five studies have addressed PA in patients with advanced-stage lung cancer. These studies have shown that increasing PA is feasible 33 and improves mobility, fatigue, sleep, pain, strength, dyspnea, anxiety, depression, and QoL, 27 , 28 , 34 , 35 though adherence may be <50%. 33 Because most patients with lung disease can perform some type of exercise with variable compliance, the potential for digital accelerometers to remotely monitor low-impact PA is appealing.…”

Section: Discussionmentioning

confidence: 99%

Assessing the Correlation Between Physical Activity and Quality of Life in Advanced Lung Cancer

Bade

Brooks

Nietert³

et al. 2016

Integr Cancer Ther

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Background and objective. Increasing physical activity (PA) is safe and beneficial in lung cancer (LC) patients. Advanced-stage LC patients are under-studied and have worse symptoms and quality of life (QoL). We evaluated the feasibility of monitoring step count in advanced LC as well as potential correlations between PA and QoL. Methods. This is a prospective, observational study of 39 consecutive patients with advanced-stage LC. Daily step count over 1 week (via Fitbit Zip), QoL, dyspnea, and depression scores were collected. Spearman rank testing was used to assess correlations. Correlation coefficients (ρ) >0.3 or <−0.3 (more and less correlated, respectively) were considered potentially clinically significant. Results. Most (83%) of the patients were interested in participating, and 67% of those enrolled were adherent with the device. Of those using the device (n = 30), the average daily step count was 4877 (range = 504-12 118) steps/d. Higher average daily step count correlated with higher QoL (ρ = 0.46), physical (ρ = 0.61), role (ρ = 0.48), and emotional functioning (ρ = 0.40) scores as well as lower depression (ρ = −0.40), dyspnea (ρ = −0.54), and pain (ρ = −0.37) scores. Conclusion. Remote PA monitoring (Fitbit Zip) is feasible in advanced-stage LC patients. Interest in participating in this PA study was high with comparable adherence to other PA studies. In those utilizing the device, higher step count correlates with higher QoL as well as lower dyspnea, pain, and depression scores. PA monitoring with wearable devices in advanced-stage LC deserves further study.

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“…Finally, 11 studies, including six RSs and five non-randomized studies (NRSs), that consisted of 922 participants were included in our systematic review. [15][16][17][18][19][20][21][22][23][24][25] We classified the selected studies as either an "intervention-control" or "before-after" study. For the intervention-control study, four of the six RSs were included.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…For the intervention-control study, four of the six RSs were included. [15][16][17][18] The other two RSs compared the exercise groups (cardiovascular vs. resistance and aerobic vs. resistance).…”

Section: Study Characteristicsmentioning

confidence: 99%

Supervised Physical Rehabilitation in the Treatment of Patients with Advanced Cancer: a Systematic Review and Meta-analysis

Yang

Choi

et al. 2020

J Korean Med Sci

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Background: As the survival rate of cancer patients increases, the clinical importance of rehabilitation provided by healthcare professionals also increases. However, the evidence supporting the relevance of rehabilitation programs is insufficient. This study aimed to review the literature on effectiveness in physical function, quality of life (QOL) or fatigue of supervised physical rehabilitation in patients with advanced cancer. Methods: A systematic review and meta-analysis was conducted following the Cochrane guidelines. We narratively described the results when meta-analysis was not applicable or appropriate. Literature databases including Ovid-MEDLINE, Ovid-EMBASE, and the Cochrane Library, as well as several Korean domestic databases, were searched up to June 2017 for studies that investigated the effectiveness of supervised physical rehabilitation programs on physical function, QOL or fatigue in patients with advanced cancer. The quality of the selected studies was evaluated independently by paired reviewers. Results: Eleven studies with 922 participants were finally selected among 2,459 articles. The meta-analysis revealed that after physical exercise, the physical activity level and strength of patients with advanced cancer increased significantly. The QOL showed a statistically significant improvement after physical rehabilitation according to the European Organization for Research and Treatment of Cancer version C30. Though some of measurements about cardiovascular endurance or strength in several studies were not able to be synthesized, each study reported that they were significantly improved after receiving rehabilitation. Conclusion: Supervised physical rehabilitation for patients with advanced cancer is effective in improving physical activity, strength, and QOL. However, more trials are needed to prove the effectiveness of supervised exercise and to strengthen the evidence.

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Pulmonary Rehabilitation in Advanced Lung Cancer Patients During Chemotherapy

Cited by 50 publications

References 14 publications

A Patient-Centered Activity Regimen Improves Participation in Physical Activity Interventions in Advanced-Stage Lung Cancer

A Patient-Centered Activity Regimen Improves Participation in Physical Activity Interventions in Advanced-Stage Lung Cancer

Assessing the Correlation Between Physical Activity and Quality of Life in Advanced Lung Cancer

Supervised Physical Rehabilitation in the Treatment of Patients with Advanced Cancer: a Systematic Review and Meta-analysis

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