Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review

Du, Xuqin; Song, Lihong; Feng, Ru; Ye, Qiao

doi:10.3389/fmed.2023.1085716

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Sarcoidosis: La sarcoidosis es una enfermedad granulomatosa sistémica de etiología desconocida, aunque se piensa que la exposición ocupacional a sustancias como la sílice y el berilio puede ser un desencadenante 25 . Una historia laboral incompleta puede conducir a un diagnóstico de sarcoidosis más que de neumoconiosis en muchos casos, aunque en la literatura se han reportado diversas asociaciones de estas dos enfermedades, como la coexistencia y detección de una antes o después de la otra.…”

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Salud Ocupacional: Mirada Normativa Para El Diagnóstico De Silicosis

Delgado-García

2023

Rev.Repub.

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Silicosis is an occupational lung fibrosis caused by the inhalation of dust containing free crystalline silica. Its prevalence can vary in different countries and regions. In the case of Chile, silicosis has been recognized as a significant occupational health problem. The clinical presentation of silicosis largely depends on the intensity and duration of exposure. Initially, there may be no signs or symptoms. The differential diagnosis is mainly performed with pulmonary tuberculosis, pulmonary aspergillosis, pulmonary metastasis, sarcoidosis, hypersensitivity pneumonitis, and other pneumoconiosis. After confirming the diagnosis, the process of determining the origin of the pathology begins, for which an Occupational History is required to describe occupational exposure to the risk agent (silica) in terms of time, magnitude, and/or intensity sufficient to develop an occupational-related disease. A Chest X-ray using the ILO (International Labour Organization) technique is necessary, classified as category 1 according to the ILO Classification, and should be interpreted by certified readers. The similarity in radiographic readings necessitates a greater emphasis on the differential diagnosis among these conditions. A high- resolution chest computed tomography without contrast and a lung biopsy should be considered in case of comorbidity, if these diagnostic tests are available. Finally, it is suggested that workers diagnosed with silicosis in the early stages should be identified and removed from silica exposure to prevent disability through medical surveillance.

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Salud Ocupacional: Mirada Normativa Para El Diagnóstico De Silicosis

Delgado-García

2023

Rev.Repub.

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Metal Toxicity and Dementia Including Frontotemporal Dementia: Current State of Knowledge

Gorini,

Tonacci

2024

Antioxidants

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Frontotemporal dementia (FTD) includes a number of neurodegenerative diseases, often with early onset (before 65 years old), characterized by progressive, irreversible deficits in behavioral, linguistic, and executive functions, which are often difficult to diagnose due to their similar phenotypic characteristics to other dementias and psychiatric disorders. The genetic contribution is of utmost importance, although environmental risk factors also play a role in its pathophysiology. In fact, some metals are known to produce free radicals, which, accumulating in the brain over time, can induce oxidative stress, inflammation, and protein misfolding, all of these being key features of FTD and similar conditions. Therefore, the present review aims to summarize the current evidence about the environmental contribution to FTD―mainly dealing with toxic metal exposure―since the identification of such potential environmental risk factors can lead to its early diagnosis and the promotion of policies and interventions. This would allow us, by reducing exposure to these pollutants, to potentially affect society at large in a positive manner, decreasing the burden of FTD and similar conditions on affected individuals and society overall. Future perspectives, including the application of Artificial Intelligence principles to the field, with related evidence found so far, are also introduced.

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Controlled and Safe Hydrogen Generation from Waste Aluminum and Water, a New Approach to Hydrogen Generation

Salueña-Berna,

Marín-Genescà,

Mujal Rosas

et al. 2024

Materials

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A new method is proposed to generate hydrogen in situ at low pressure from powder-pressed recycled aluminum turnings activated with small amounts of NaOH and drops of water. The contribution of this system is that the user can obtain small flows of high-purity hydrogen (>99%) to charge their portable electronic devices in remote places, in a simple, controlled, and safe way, since only water is used. Test tubes that contain tiny amounts of NaOH on their surface can be transported and used without contact. In addition to being a safer system, a smaller amount of NaOH and water is needed compared to other systems, there is no need to preheat the water, and the system can even generate heat. As the feeding is drop by drop, the hydrogen flow can be easily controlled by manual or automatic dosing. The waste obtained is solid and contains mostly aluminum hydroxide with some NaOH and impurities from the waste of origin, which are easy to sell and recycle. A study has been carried out to optimize the type of test tubes and establish critical parameters. The results show that a constant and controllable flow rate of hydrogen can be obtained depending on the drip frequency where the chemical reaction predominates over diffusion, that the optimal amount of NaOH is 20 wt%, that a finer grain size can increase the H2 yield with respect to the stoichiometric value but reduces the instantaneous flow with respect to that obtained with larger grains, and that it is very important to control the density and the impurities to increase porosity and therefore water diffusion. The estimated cost of the hydrogen produced is 3.15 EUR/kgH2 and an energy density of 1.12 kWh/kg was achieved with a test tube of 92% aluminum purity and 20 wt% NaOH.

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Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review

Cited by 3 publications

References 24 publications

Salud Ocupacional: Mirada Normativa Para El Diagnóstico De Silicosis

Salud Ocupacional: Mirada Normativa Para El Diagnóstico De Silicosis

Metal Toxicity and Dementia Including Frontotemporal Dementia: Current State of Knowledge

Controlled and Safe Hydrogen Generation from Waste Aluminum and Water, a New Approach to Hydrogen Generation

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