Pulmonary sarcoidosis: correlation of CT and histopathologic findings.

Nishimura, Koichi; Itoh, Hideto; Kitaichi, Masanori; Nagai, Sonoko; Izumi, Tohru

doi:10.1148/radiology.189.1.8372178

Cited by 169 publications

(96 citation statements)

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“…(100) Pathologic correlation of ground-glass opacity in patients with sarcoidosis has shown that conglomerate granulomas can occur, as can delicate fibrosis below the limits of HRCT resolution. (101)(102)(103) Consolidations, mimicking OP, are uncommon in sarcoidosis. (104) The presentation is acute and the prognosis is excellent.…”

Section: Sarcoidosismentioning

confidence: 99%

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

et al. 2008

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High-resolution computed tomography (HRCT) is the radiological imaging technique best suited to revealing changes in lung structure. Various HRCT findings, taken together, can represent typical patterns. These patterns, in conjunction with the anatomical distribution of findings and with clinical data, can narrow the differential diagnosis of diffuse interstitial lung disease and, in many cases, indicate the correct diagnosis with a high degree of accuracy. The most common HRCT patterns seen in cases of diffuse interstitial lung diseases are the nodular pattern, linear/reticular opacities, cystic lesions, ground-glass opacities and consolidations. This article reviews the correlations between HRCT patterns and pathologic findings, summarizing the most common causes, as well as detailing the methods of investigation employed in order to diagnose the most common types of chronic diffuse lung disease.Keywords: Lung diseases, interstitial/pathology; Tomography, X-Ray computed; Diagnostic techniques, respiratory system. ResumoA tomografia de alta resolução (TCAR) é a técnica de imagem radiológica que reflete mais de perto as alterações da estrutura pulmonar. Os vários achados tomográficos podem ser combinados para formar padrões típicos. Estes, conjuntamente com a distribuição anatômica dos achados, e com os dados clínicos, podem estreitar o diagnóstico das doenças intersticiais pulmonares difusas, e em vários casos sugerir o diagnóstico correto com alto grau de acurácia. Os padrões mais comuns das doenças intersticiais pulmonares difusas na TCAR são o nodular, linear e reticular, lesões císticas, opacidades em vidro fosco e consolidações. Este artigo revisa as correlações entre os padrões tomográficos na TCAR e os achados patológicos e resume as causas mais comuns e os métodos de investigação para se atingir um diagnóstico nas doenças pulmonares crônicas difusas mais comuns.Descritores: Doenças pulmonares intersticiais/patologia; Tomografia computadorizada por raios X; Técnicas de diagnóstico do sistema respiratório.* Study carried out in the

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Section: Sarcoidosismentioning

confidence: 99%

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

et al. 2008

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“…Consolidation has revealed alveolitis with inflammatory exudates in alveolar spaces and/or accumulated granulomatous lesions [29][30][31]. In the present report, biopsy specimens corresponding to consolidation could not be obtained, and whether consolidation shows alveolitis or granulomatous lesions remains unclear.…”

Section: Discussionmentioning

confidence: 62%

“…CT findings are considered to correspond to granulomas, with or without perigranulomatous fibrosis, formed in the connective tissue sheath around the bronchial walls, pulmonary vessels and airways [29]. Thus, our results might be due to perigranulomatous fibrosis with granulomas.…”

Section: Discussionmentioning

confidence: 63%

Comparison of pulmonary thin section CT findings and serum KL-6 levels in patients with sarcoidosis

Honda¹,

Okada²,

Ando³

et al. 2011

BJR

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“…They are typically scattered throughout the interstitium of the lungs, along the lymphatics, particularly in the peribronchovascular and subpleural spaces, and along the interlobular septa. Pathologically, noncaseating granulomas distribute mostly along the lymphatics in the peribronchovascular sheath and, to a lesser extent, in the subpleural and interlobular septal lymphatics 6,7 . However, the diseases in lymphatic and perilymphatic distribution include lymphangitic carcinomatosis, lymphoproliferative disease, silicosis, and amyloidosis as well as sarcoidosis.…”

Section: Discussionmentioning

confidence: 99%

A Pulmonary Sarcoidosis Manifesting as a Rare Atypical Pattern and Distribution

et al. 2008

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A unique case of atypical pulmonary sarcoidosis in a 62-year-old man complaining of dyspnea is presented. Chest CT scan showed an unusual pattern and distribution of pulmonary sarcoidosis manifesting mainly as reticular densities, interlobular septal thickening, and ground-glass opacities, in the subpleural and lower lung predominancy. However, a surgical lung biopsy revealed classical findings of sarcoidosis. Knowledge of this atypical pulmonary involvement may improve understanding sarcoidosis as the great masquerader. (Tuberc Respir Dis 2008;64:236-239)

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Pulmonary sarcoidosis: correlation of CT and histopathologic findings.

Abstract: CT is a valuable technique with which to visualize the characteristic location of sarcoid granulomas in the pulmonary parenchyma.

Cited by 169 publications

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Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

Comparison of pulmonary thin section CT findings and serum KL-6 levels in patients with sarcoidosis

A Pulmonary Sarcoidosis Manifesting as a Rare Atypical Pattern and Distribution

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