Pulmonary Tuberculoma Evaluated by Means of FDG PET: Findings in 10 Cases

Goo, Jin Mo; Im, Junq Gi; Hyun, Kyung Hee; Yeo, Jun Sang; Seo, Joon Beom; Kim, Hyae Young; Chung, June Key

doi:10.1148/radiology.216.1.r00jl19117

Cited by 321 publications

(203 citation statements)

References 17 publications

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“…However, FDG-PET has given false-negative results for well-differentiated pulmonary adenocarcinoma (Higashi et al, 1998;Cheran et al, 2004), or small volumes of metabolically active tumor (Satoh et al, 2011), and false-positive results for inflammatory nodules (Goo et al, 2000;Nomori et al, 2004). In addition, FDG-PET is not widely available because of its high cost.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Performance of Diffusion Weighted Imaging of Malignant and Benign Pulmonary Nodules and Masses: Comparison with Positron Emission Tomography

Usuda

Sagawa

Motono

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 99%

Diagnostic Performance of Diffusion Weighted Imaging of Malignant and Benign Pulmonary Nodules and Masses: Comparison with Positron Emission Tomography

Usuda

Sagawa

Motono

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Moreover, they found that the highest [5][6][7]. However, some benign inflammatory lesions could show F-18 FDG accumulation yielding false positive findings [22][23][24].…”

Section: Discussionmentioning

confidence: 99%

Characterization of Pulmonary Lesions with Low F-18 FDG Uptake Using Double Phase F-18 FDG PET/CT: Comparison of Visual and Quantitative Analyses

Ij¹,

Sj²,

Kim³

et al. 2009

neo

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Background of the present study was to assess the usefulness of double phase positron emission tomography/computed tomography (peT/CT) to differentiate malignant from benign pulmonary lesions with low fluorine-18 fluorodeoxyglucose (F-18 FDG) uptake.of 218 consecutive patients who underwent double phase F-18 FDG peT/CT to evaluate pulmonary lesions found on CT, we retrospectively analyzed 30 who had focal pulmonary lesions with an sUV of <2.5. all patients underwent peT/CT of the thorax at two time points: scan 1 at 60 min and scan 2 at 120 min after the intravenous injection of 2.5 mBq F-18 FDG. The F-18 FDG peT/CT images were analyzed visually and quantitatively.of 30 evaluated nodules, 13 (43%) proved to be malignant and 17 (57%) benign. The sUV max1 (maximal sUV of early image), sUV max2 (maximal sUV of delayed image), %∆sUV max (percent change of maximal sUV), CR 1 (contrast ratio of early image), and CR 2 (contrast ratio of delayed image) of malignant pulmonary lesion were significantly higher than those of benign. However, %∆CR (percent change of contrast ratio) revealed no statistical differences. among the quantitative indices, sUV max1 , sUV max2 , and CR 2 were superior to the visual analysis for differentiation of malignant from benign pulmonary lesions. The sUV max1 , sUV max2 , and %∆sUV max were superior to %∆CR for differentiation of malignant from benign pulmonary lesions.Based on the presented results, the quantitative indices except %∆CR were higher in malignant nodules than benign pulmonary nodules. However, the diagnostic performances were similar between visual and quantitative analyses. Further studies are needed to confirm these results and improve statistical accuracy.

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“…tense FDG uptake (1). However, it is rare that FDG-PET scans revealed partial intense FDG uptake in the nodule.…”

Section: P I C T U R Ementioning

confidence: 99%

A Rare Image of a Pulmonary Nodule Revealed on FDG-PET Scans

et al. 2010

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A 49-year-old man with well-controlled diabetes was admitted to our hospital for medical examination concerning a nodular lesion with a diameter of approximately 2 cm with a well-defined margin at the S3 region of the left lung. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) scans (Picture 1) and PET-CT (Picture 2) revealed partially intense FDG uptake with a maximum standardized uptake value of 5.1 in the nodule. Biopsy of the nodule was performed as a video-assisted thoracoscopic surgery to establish diagnosis. The resected specimen disclosed that the majority of the nodule was necrotic (Picture 3). The histological findings were established as epithelioid cell granuloma with caseous necrosis (Picture 4). Furthermore, the bacteriological examination stained with Ziehl-Neelsen disclosed the existence of acid-fast bacteria.FDG-PET scan is a useful method for the detection of malignancy, however it is not confirmatory for the detection of only malignant diseases. In particular, it is well known that the epithelioid cell granuloma can demonstrate an in-

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Pulmonary Tuberculoma Evaluated by Means of FDG PET: Findings in 10 Cases

Abstract: Pulmonary tuberculoma commonly causes an increase in FDG uptake. These results suggest that in geographic regions with a high prevalence of granulomatous lesions, positive FDG PET results should be interpreted with caution in differentiating benign from malignant pulmonary abnormalities.

Cited by 321 publications

References 17 publications

Diagnostic Performance of Diffusion Weighted Imaging of Malignant and Benign Pulmonary Nodules and Masses: Comparison with Positron Emission Tomography

Diagnostic Performance of Diffusion Weighted Imaging of Malignant and Benign Pulmonary Nodules and Masses: Comparison with Positron Emission Tomography

Characterization of Pulmonary Lesions with Low F-18 FDG Uptake Using Double Phase F-18 FDG PET/CT: Comparison of Visual and Quantitative Analyses

A Rare Image of a Pulmonary Nodule Revealed on FDG-PET Scans

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