Pulmonary tuberculosis in its pseudotumoral form; one new case

Herrak, L.; Amangar, N.; Berri, K.; Begnani, M. El; Ftouh, M. El; Fihry, M.T. El Fassy

doi:10.1016/j.ejcdt.2013.08.007

Cited by 5 publications

(6 citation statements)

References 4 publications

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“…These unusual patterns are largely responsible for misdiagnosis or delayed diagnosis resulting in increased mortality and morbidity. 5 , 6 , 9 It has been estimated that about 3 – 6% of pulmonary TB may present as non-calcified mass lesions which are best characterized on chest CT-scan usually measuring between 5 mm to 40 mm in the largest diameter. 18 Similarly the cases presented here were both immunocompetent individuals who presented unusually with lung masses of 35 mm and 70 mm in their largest diameter.…”

Section: Discussionmentioning

confidence: 99%

“…18 The manifestation of PTB as a lung mass is quite rare in immunocompetent individuals and differentiation from a primary lung cancer becomes challenging especially when repeated negative sputum smears for acid -fast bacilli, sputum culture for MTB and GeneXpert occurs. 6,11 Conversely, lung cancer can also be misdiagnosed as PTB, particularly in the regions of the world where tuberculosis is endemic with a very high burden. 16,19 Anecdotal evidence in our environment adds credence to this observation as a significant proportion of primary lung cancer cases receive prior TB treatment delaying the diagnosis with abysmal outcomes.…”

Section: Discussionmentioning

confidence: 99%

“… 4 , 5 Pseudotumoural pulmonary tuberculosis is rare and occurs in 3.5 % to 4.5 % of immunocompetent patients even in TB endemic regions of the world. 6 , 7 …”

Section: Introductionmentioning

confidence: 99%

“…4,5 Pseudotumoural pulmonary tuberculosis is rare and occurs in 3.5 % to 4.5 % of immunocompetent patients even in TB endemic regions of the world. 6,7 Diagnosis is usually challenging because of non-specific clinical features and radiological similarities to lung cancer and other lung pathologies. 8,9 Short course anti-tuberculous treatment as for other forms of pulmonary tuberculosis consisting of isoniazid (INH), rifampicin (RIF), ethambutol (EMB) and pyrazinamide (MPZ) has been found to be effective in controlling the disease and reducing the size of the mass.…”

Section: Introductionmentioning

confidence: 99%

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Pseudotumour presentation of pulmonary tuberculosis

Afriyie-Mensah

Awindaogo

Asomani

2020

gmj

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Pulmonary tuberculosis manifesting as a mass lesion, thus, mimicking a lung carcinoma is an unusual radiographic presentation of tuberculosis (TB). The common radiologic patterns and clinical presentations are well known and documented. We report two cases of pulmonary tuberculosis with a neoplastic appearance on chest imaging diagnosed histologically. A 21 – year old female with cough, weight loss, anorexia and an unremarkable physical examination. Chest radiography showed a right apical mass suggestive of lung cancer. Histology of the lesion revealed parenchymal pulmonary tuberculosis. A 49–year old male with left-sided chest pain, cough, anorexia, weight loss, mild pallor with an unremarkable chest examination. Chest imaging showed a left apical mass and mediastinal lymphadenopathy. Microscopic examination of the mass confirmed pulmonary tuberculosis. Pseudotumour pulmonary tuberculosis is a rare clinical entity that can lead to diagnostic challenges and must be considered in the differential diagnosis when mass lesions are seen on chest imaging, especially in TB endemic areas.Keywords: tuberculosis, pulmonary, carcinoma, atypical, diagnosticFunding: None declared

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“… 4 , 5 Pseudotumoural pulmonary tuberculosis is rare and occurs in 3.5 % to 4.5 % of immunocompetent patients even in TB endemic regions of the world. 6 , 7 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pseudotumour presentation of pulmonary tuberculosis

Afriyie-Mensah

Awindaogo

Asomani

2020

gmj

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“…Data on parenchymal pseudotumoral form tuberculosis are poor and just a few cases have been reported in literature. [9][10][11][12] Herein in this case report showing a pulmonary pseudotumoral tuberculosis in an old immunocompetent patient we stressed the rarity of the disease and the difficulties in the diagnosis that leaded to a delay in therapy. This case report underlines that pulmonary tuberculosis can present like mass lesion mimicking bronchogenic carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary pseudotumoral tuberculosis in an old man: A rare presentation

Campobasso

Perrone

D’Introno

et al. 2017

CRIM

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The pseudotumoral form of tuberculosis is very rare in healthy immunocompetent subjects and can simulates lung carcinoma causing diagnosis dilemma or lead to abusive surgical resection. Here we report a case of pulmonary tuberculosis in its pseudotumoral form in an immunocompetent old men who presented with cough, fatigue and fever. A computerized tomography of the chest indicated a dishomogeneous mass that compressed and deformed the left main bronchus that was referable to a primary tumor. The hystopatological exam from the bioptic samples obtained by bronchoscopy was negative for neoplasia. Moreover, an abdomen CT scan showed hypodense solid lesions of the liver likely to be considered as metastasis; the histological analysis of these hepatic lesions was negative for neoplasia. It was necessary to perform a second CT scan of the chest and another bronchoscopy with biopsy and histopathological examination before establishing the diagnosis of the pulmonary pseudotumoral form. The case report confirm, as previously described, the difficulties in the diagnosis of this rare form of tuberculosis that lead to a delay in therapy, and suggest that the pseudotumor has to be included as different diagnosis of pulmonary mass also in healthy immunocompetent subjects.

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