Pulmonary Vein Isolation with a New Multipolar Irrigated Radiofrequency Ablation Catheter (nMARQ™): Feasibility, Acute and Short‐Term Efficacy, Safety, and Impact on Postablation Silent Cerebral Ischemia

Abstract

Background: Simultaneous multipolar ablation catheters have been proposed to simplify

Acute and Mid-Term Results after Pulmonary Veins Isolation Using a Novel Circular Irrigated Multielectrode Mapping and Ablation Catheter (nMARQ)

“…The acute success rate found in this study and reported in recent studies using the novel nMARQ TM catheter [5] [7] [8] compares with the acute success rate reported by previous studies using a conventional, single-tip approach guided by a 3D mapping system [9], cryoballoon [3], a visually guided laser balloon catheter [10], or PVAC [4].…”

“…Overall, 100% targeted PVs could be isolated without procedure-related complications. In other study 25 patients with PAF underwent PVI using the nMARQ TM catheter [7]. The ablation was guided by electroanatomic map created by nMARQ TM and merged with the 3-D magnetic resonance imaging (MRI) shell of LA.…”

“…The deployment of nMARQ TM catheter into right inferior PV can be challenging specially if it is small. Confirmation of PVI was achieved using mainly the nMARQ TM catheter in some studies [5] [8], while Lasso catheter was used in others [7].…”

Safety and efficacy of pulmonary vein isolation using a circular, open-irrigated mapping and ablation catheter: A multicenter registry

“…Deneke et al (7,13) reported one esophago-pericardial fistula, a high incidence of mild thermal esophageal lesions, and an incidence of silent cerebral lesions higher than single-tip irrigated RF. However Scaglione et al (12), using a specific and cautious procedural workflow, observed the complete absence of periprocedural silent cerebral ischemia. In our series no stroke/TIA, pericardial effusion, or cardiac tamponade were observed.…”

“…Few data are available on the follow-up. In the Scaglione et al (12) series 17/25 (68%) patients with paroxysmal AF were free from AF without antiarrhythmic drugs at a 6-month follow-up; in the Shin et al (10) series, after 3 months, sinus rhythm was stable off antiarrhythmic drugs in 17 of 21 (80.9%) patients; in the Zellerhof et al (11) series single and multiple procedure success rates during a mean follow-up of 140+75 days were 66 and 77%, respectively. In our cohort the freedom of atrial arrhythmias was similar at a longer follow-up (13.9 months) and also patients with persistent AF showed a recurrence rate of 30%.…”