Pulpal Reaction to Bleaching of Teeth in Dogs

Seale, N. Sue; McIntosh, J. E. A.; Taylor, A. N.

doi:10.1177/00220345810600051701

Cited by 101 publications

(88 citation statements)

References 9 publications

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“…1,6 The present study also showed a cytotoxic effect of the substances released by the bleaching gel, that was transient once the laser irradiation was able to offset this effect. In fact, different levels of cellular response to substances released by the bleaching agent were observed.…”

Section: Discussionsupporting

confidence: 60%

“…[2][3][4] When it reaches the pulp chamber, it can trigger reversible inflammation. 5,6 Tooth bleaching agents, carbamide peroxide or hydrogen peroxide, undergo ionization and decay, producing free radicals. Free radicals are highly unstable and exhibit remarkable ability to react with other organic substances 7 and may even cause damage to cellular DNA.…”

Section: Introductionmentioning

confidence: 99%

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In vitro effect of low intensity laser on the cytotoxicity produced by substances released by bleaching gel

et al. 2010

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This in vitro study aimed to analyze the effect of different parameters of phototherapy with low intensity laser on the viability of human dental pulp fibroblasts under the effect of substances released by bleaching gel. Cells were seeded into 96 wells plates (1 x 10 3 cells/well) and placed in contact with culture medium conditioned by a 35% hydrogen peroxide bleaching gel for 40 minutes, simulating the clinical condition of the in-office bleaching treatment. Cells cultured in ideal growth conditions served as positive control group (PC), and the cells grown in conditioned medium and non-irradiated served as negative control group (NC). Cells grown in conditioned medium were submitted to a single irradiation with a diode laser (40 mW, 0.04 cm²) emitting at visible red (660 nm; RL) or near infrared (780 nm; NIR) using punctual technique, in contact mode and energy densities of 4, 6 or 10 J/cm². The cell viability was analyzed through the MTT reduction assay immediately and 24 hours after the irradiation. The data was compared by ANOVA followed by the Tukey's test (p ≤ 0.05). The cell viability increased significantly in 24 hours within each group. The PC presented cell viability significantly higher than NC in both experimental times. Only the NIR/10 J/ cm² group presented cell viability similar to that of PC in 24 hours. The phototherapy with low intensity laser in defined parameters is able to compensate the cytotoxic effects of substances released by 35% hydrogen peroxide bleaching gel.

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Section: Discussionsupporting

confidence: 60%

Section: Introductionmentioning

confidence: 99%

In vitro effect of low intensity laser on the cytotoxicity produced by substances released by bleaching gel

et al. 2010

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“…However, it is known that the aggressiveness of a bleaching gel depends not only on its application time on enamel (10), but also on the H 2 O 2 concentration in the product. The increase of the bleaching time may result in a deeper penetration of the components released from the bleaching gel, which may cause severe damage to the pulp tissue (10,18). The penetration of H 2 O 2 -based bleaching agents into the dental structure causes different alterations in vital teeth (3) and some products resulting from H 2 O 2 degradation, such as OH -and other ROS, may cause lipid peroxidation and protein fragmentation with consequent cell membrane damage (9).…”

Section: Discussionmentioning

confidence: 99%

“…A previous study showed that the application of a 33% H 2 O 2 bleaching gel for 30 min on the enamel of canine teeth was capable to produce damage to odontoblast-like cells and internal inflammatory root resorption (10). In the present study, in addition to us- ing teeth with structural characteristics and hard tissue thickness similar to those of human teeth, a long total bleaching time was established (75 min, distributed in five 15-min consecutive applications) in order to simulate a frequent clinical situation in vital tooth bleaching therapies to whiten severely darkened teeth.…”

Section: Discussionmentioning

confidence: 99%

Indirect cytotoxicity of a 35% hydrogen peroxide bleaching gel on cultured odontoblast-like cells

et al. 2009

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The aim of this study was to evaluate the trans-enamel and trans-dentinal effects of a 35% hydrogen peroxide (H 2 O 2 ) bleaching gel on odontoblast-like cells. Enamel/dentin discs obtained from bovine incisors were mounted in artificial pulp chambers (APCs). Three groups were formed: G1-35% H 2 O 2 ; G2-35% H 2 O 2 + halogen light application; G3-control. The treatments were repeated 5 times and the APCs were incubated for 12 h. Then, the extract was collected and applied for 24 h on the cells. Cell metabolism, total protein dosage and cell morphology were evaluated. Cell metabolism decreased by 62.09% and 61.83% in G1 and G2, respectively. The depression of cell metabolism was statistically significant when G1 and G2 were compared to G3. Total protein dosage decreased by 93.13% and 91.80% in G1 and G2, respectively. The cells in G1 and G2 exhibited significant morphological alterations after contact with the extracts. Regardless of halogen light application, the extracts caused significantly more intense cytopathic effects compared to the control group. After 5 consecutive applications of a 35% H 2 O 2 bleaching agent, either catalyzed or not by halogen light, products of gel degradation were capable to diffuse through enamel and dentin causing toxic effects to the cells.

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“…Carrasco ve arkadaşları 12 yaptığı çalışma sonucunda kullandıkları diyot Lazer, plazma ark lambası, kuartz tungsten halojen ışık kaynaklarının LED' e kıyasla yüksek pulpa odası sıcaklık artışlarına neden olduğunu bildirmişlerdir. Sarı ve arkadaşları 13 16 Rhesus maymunlarında yaptıkları çalışmalarda; 2, 14, 56 ve 93 günlük periyotlar sonunda bilinen yüzeysel ısı artışlarını histolojik olarak gözlemlenebilir pulpal hasarlarla alakalandırmışlar ve bu amaçla pulpa duvarında istenilen sıcaklığa ulaşana kadar sağlıklı bir dişin bukkal yüzeyine 275 ° C ' lik lehim uygulamışlardır. Bu çalışmanın sonuçlarına göre 5.5 °C ısıtılan dişlerin %15' inin ve 11.1 °C ısıtılan dişlerin % 60' ının irreversibl hasar aldığını bildirmişlerdir.…”

Section: Introductionunclassified

The Effect Of Light-Activated Bleaching On Increase Of Pulp Chamber Temperatures

Kılınç¹,

Türkün²

2016

EÜ Dişhek Fak Derg

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ÖZET Amaç: Bu çalışmanın amacı, çeşitli ışık kaynakları kullanarak yapılan diş beyazlatma işlemi sırasında beyazlatma jeli varlığında ve yokluğunda pulpa odasındaki sıcaklık artışını değerlendirmektir. Yöntem: Çalışmada 20 adet yeni çekilmiş insan dişi kullanıldı. Kuartz tungsten halojen ışık kaynağı, LED ışık kaynağı ve diode Lazer ışık kaynağı kullanılarak beyazlatma ajanı (%36 H2O2) varlığında ve yokluğunda olmak üzere dişler 15 dakika boyunca ışığa maruz bırakıldı ve oluşan pulpa odası sıcaklık artışları kaydedildi. Veriler Paired Simple test, Univariate Analysis of Varianca ( ANOVA ), Dependet Variable Test ve Tukey ' s honestly significant difference ( HSD ) ile istatistiksel olarak analiz edildi. Bulgular: Diode lazer ışık kaynağı en yüksek ışı artışına neden oldu. LED ışık kaynağı ise en düşük ısı artışına neden oldu. İstatistiksel analizler ışık kaynakları arasında, sıcaklık artışında istatistiksel olarak anlamlı derecede farklılık olduğunu gösterdi (P=.000). Sonuç: Araştırmamıza göre, LED ve halojen ışık kaynakları pulpada ısı artışına neden olmuştur fakat bu artış pulpa dokusunda geri dönüşümsüz zararlı değişikliğe neden olacak seviyede değildir. Fakat, diode lazer ışık kaynağı kullanıldığında fazla ısı artışı olabilmesi nedeniyle dikkatli olunması gerekir. Bu sonuçlar, diş tiplerinden ve beyazlatma ajanı varlığından etkilememiştir. Anahtar Kelimeler: Sıcaklık artışı, LED, halojen ışık, lazer, aktivatör ışık, diş beyazlatma, pulpa

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Pulpal Reaction to Bleaching of Teeth in Dogs

Cited by 101 publications

References 9 publications

In vitro effect of low intensity laser on the cytotoxicity produced by substances released by bleaching gel

In vitro effect of low intensity laser on the cytotoxicity produced by substances released by bleaching gel

Indirect cytotoxicity of a 35% hydrogen peroxide bleaching gel on cultured odontoblast-like cells

The Effect Of Light-Activated Bleaching On Increase Of Pulp Chamber Temperatures

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