Pulsed dye laser: what's new in non‐vascular lesions?

Karsai, Syrus; Roos, Susanne; Hammes, Stefan; Raulin, Christian

doi:10.1111/j.1468-3083.2007.02297.x

Cited by 64 publications

(51 citation statements)

References 89 publications

(123 reference statements)

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“…23,24 Several studies have reported the improvement of the clinical appearance of striae with 585-nm pulsed dye laser (PDL) via enhancement of the extracellular matrix collagen. [25][26][27][28] In addition, it has a modest efficacy in decreasing the erythema of striae rubra; however, it has [29][30][31][32] More recently, there has been evidence that indicates the benefits of both fractionated non-ablative and ablative lasers in increasing collagen fibers, and improving the appearance of striae alba. Our study aimed to assess the effectiveness a fractionated CO 2 in the treatment of striae alba, especially in darker skin types.…”

Section: Introductionmentioning

confidence: 99%

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

et al. 2017

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Introduction: In recent years, the positive effect of fractional CO 2 laser on increasing collagen fibers, and consequently its effect on treating striae has been suggested. The present study aims to assess the effectiveness of CO 2 fractional laser 10600-nm in the treatment of striae alba. Methods: In this prospective clinical trial, 2 treatment sessions of fractional CO 2 laser with 4-week interval was given to 30 patients with striae alba. Cutaneous resonance running time (CRRT) was measured at baseline and at week 4 and 3 months after the last session of laser therapy. The level of improvement was assessed by 2 independent dermatologists and patients after 3 months of follow up. Results: 16.7% of patients had moderate improvement, 63.3% had minimal improvement, and 20% had no improvement. A statistical significant difference was found in median CRRT during the study (P < 0.0001). The median CRRT levels were significantly higher in week 4 and 3 months after the last treatment compared to the baseline (both P < 0.001). Likewise, a significant increase was observed in median CRRT level from week 4 till the end of study (P < 0.001). Evaluation of participant satisfaction revealed that 10% were very satisfied, 10% satisfied, 3.3% slightly satisfied, and 76.7% unsatisfied. Conclusion: Striae alba remain a challenging condition to treat. The treatment of striae alba with CO2 fractional laser results in minimal improvement with mild side effects.

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Section: Introductionmentioning

confidence: 99%

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

et al. 2017

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“…Bulafl›c› olmas› nedeniyle toplumda ve özellikle pediatrik-adult döneminde görülme s›kl›¤› %10 civar›ndad›r 2,3 . HPV, DNA virüsüdür ve HPV'nin 100'den fazla genotipi tespit edilmifltir 4,5 .…”

Section: Giriflunclassified

The Efficiency of 1064 nm Nd: YAG Laser in the Treatment of Different Types of Verruca

Saçar¹,

Saçar²

2010

turkderm

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Klinik iyileflme de¤erlendirilmesinde % 75-100 aras› iyileflme oran› %97, hasta memnuniyeti aç›s›ndan %50'nin üzerinde iyileflme oran› % 98,5 olarak tespit edildi. Bulgular›m›z ve yan etki oranlar›m›z literatür bulgular› ile örtüflmektedir. Sonuç: Di¤er tedavi yöntemleri ile karfl›laflt›rd›¤›m›zda 1064 nm Nd YAG lazer ile tedavi baflar› oran› oldukça yüksek olup a¤-r› d›fl›nda yan etki potansiyeli de fazla de¤ildir. Sistemin dezavantaj› pahal› olmas›d›r. ‹¤ne korkusu olanlarda, çocuklarda, uzun süren lokal tedavi istemeyenlerde en etkili, en az zaman kayb›na yol açan yöntem oldu¤u düflüncesindeyiz. (Türkderm 2010; 44: 156-9) Anahtar Kelimeler: Nd YAG 1064 nm lazer, tedavi, si¤il, viral si¤iller. SummaryBackground and Design: The aim of this study was to determine the efficiency of 1064 nm Nd:YAG laser in different types of verruca. Material and Method: A prospective descriptive study was planned. The study group constituted of 198 patients who had referred to the dermatology outpatient clinic between September 2007 and September 2008 with warts located at different sites and not previously treated. Results: Of the 198 patients aged 7-65 years who applied to our outpatient clinic during the study, 83 (41.9%) were female, 115 (58.1%) were male and the female/male ratio was 0.72; the total wart number, the mean wart number, and standard deviation were found to be 1127, 6.59, and 14.28, respectively. The location of warts was as follows: periungual (n=25; 12.6%), facial -plana (n=16; 8.1%), palmar (n=45; 22.7%), plantar (n=70; 35.4%), and genital (n=42; 21.2%). At clinical recovery evaluation, the recovery rate was 97% (range: 75-100%), and the patient satisfaction was found to be 98.5% in recovery rate over 50%. Our results and the rate of side effects overlap with those in the literature. Conclusion:The treatment success ratio with 1064 nm Nd:YAG laser is quite high in comparison with the other treatment methods and its side effects are not too much, except for pain. Being expensive is the disadvantage of the system. We suggest that Nd:YAG laser is the most efficient and time-saving method in patients with needle fear, unwilling to receive longstanding local treatment, and in children. (Turkderm 2010; 44: 159-6)

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“…Dermatological lesions that represent the target may be considered typical vascular lesions, vascular dependent lesions, or nonvascular lesions, according to a recent classification [1]. …”

Section: Introductionmentioning

confidence: 99%

“…Nonvascular lesions, on the other hand, include viral infections like molluscum contagiosum as well as other cutaneous conditions, for example, xanthelasma palpebrarum [1–13]. …”

Section: Introductionmentioning

confidence: 99%

Nonconventional Use of Flash-Lamp Pulsed-Dye Laser in Dermatology

Nisticò

Campolmi

Moretti

et al. 2016

BioMed Research International

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Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement. In particular, 149 patients (73 males and 76 females) were treated. They were affected by the following dermatological disorders: angiokeratoma circumscriptum, genital and extragenital viral warts, striae rubrae, basal cell carcinoma, Kaposi's sarcoma, angiolymphoid hyperplasia, and Jessner-Kanof disease. They all underwent various laser sessions. 89 patients (59.7%) achieved excellent clearance, 32 patients (21.4%) achieved good-moderate clearance, 19 patients (12.7%) obtained slight clearance, and 9 subjects (6.1%) had low or no removal of their lesion. In all cases, FPDL was found to be a safe and effective treatment for the abovementioned dermatological lesions in which skin microvessels play a role in pathogenesis or development. Further and single-indication studies, however, are required to assess a standardized and reproducible method for applying this technology to “off-label” indications.

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Pulsed dye laser: what's new in non‐vascular lesions?

Abstract: With PDL, it is possible to achieve good results with numerous, partly less well-known indications (i.e. lupus erythematosus). With other diseases, PDL has so far been considered to be a complementary therapy method or to be in an experimental state.

Cited by 64 publications

References 89 publications

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

The Efficiency of 1064 nm Nd: YAG Laser in the Treatment of Different Types of Verruca

Nonconventional Use of Flash-Lamp Pulsed-Dye Laser in Dermatology

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