The total influence of self-phase modulation, phase cross-modulation and four-wave mixing effects and amplified spontaneous emission noise on transmitted pulsed signals noise immunity in a multichannel fiberoptic transmission system with spectral division multiplexing is investigated. The investigation is carried out under the conditions of transmitting system parameters variation: the total optical power level in optical fiber, the transmission speed and the number of spectral channels. The estimate criterion of transmitted pulsed signals noise immunity is Q-factor. The total Q-factor value dependence on the total optical power level in optical fiber for various transmission speed and the number of spectral channels is demonstrated.