Pumice-based sulfonic acid: a sustainable and recyclable acidic catalyst for one-pot synthesis of pyrazole anchored 1,4-dihydropyridine derivatives at room temperature

Tambe, Adinath; Sadaphal, Gayatri; Dhawale, Ravindra; Shirole, Gopinath D.

doi:10.1007/s11164-021-04649-7

Cited by 6 publications

(2 citation statements)

References 49 publications

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“…The advantages of the use of these catalytic materials are low cost, no toxicity, high porosity and heterogeneous nature which removes the obstacles in the scale up process of the reaction. 6 In the last decades, 1,8-dioxo-octahydroxanthenes have much more interest due to its important applications in dyes industries, laser industries and also some derivative has been used for visualisation of bio-molecules with the view of its fluorescent properties. [7][8][9][10] Xanthendione are found as an important core in various natural products.…”

Section: Introductionmentioning

confidence: 99%

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Efficient and reusable Pumice supported perchloric acid catalyst for concise and effective synthesis of 1,8-dioxo-octahydroxanthenes under solvent free condition

Tambe,

Shirole,

Dange

et al. 2024

10.5267/j.ccl

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In the present investigation, a library of 1,8-dioxo-octahydroxanthene derivatives have been synthesised by the cyclo-condensation reaction of aryl aldehyde with two moles of dimedone under solvent free condition in the presence of Novel Pumice supported perchloric acid (Pumice@HClO4) as a less expensive, recyclable, thermodynamically stable and non-toxic catalyst. The significant advantages of this novel protocol are experimental simplicity, easy work-up procedure, good to excellent yields of product and more sustainable as the efficiency of the readily available catalytic material.

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Section: Introductionmentioning

confidence: 99%

“…Physical and SpectralData 3,4,6,3,6,tetramethyl-9-p-tolyl-2H-xanthene-1,8(5H,9H)-dione (3a):Yield 85%; m.p. 210-212°C; FT-IR (ν in cm -1 ): 2961.36 (-CH), 1658.21 (-C=O), 1509.46 (C=C), 1217.10 (-C-O); 1 H NMR (500 MHz, CDCl3, ppm): δ 0.97 (s, 6H, -CH3 X 2), 1.09 (s, 6H, -CH3 X 2), 2.17…”

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confidence: 99%