2010
DOI: 10.3109/02770903.2010.528500
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Pumpless Extracorporeal Lung Assist for the Treatment of Severe, Refractory Status Asthmaticus

Abstract: This report suggests that pECLA is an alternative extracorporeal lung assist in patients with ventilation-refractory hypercapnia and respiratory acidosis due to severe, refractory status asthmaticus.

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Cited by 25 publications
(12 citation statements)
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“…Much of the evidence in support of its use in status asthmaticus is based on case reports with the reported indications in this group ranging from cardiovascular compromise, cardiac arrest, hypoxemia and shock, severe hypercap nia and acidosis, to dynamic hyperinflation [2, 6,7].…”
Section: Discussionmentioning
confidence: 99%
“…Much of the evidence in support of its use in status asthmaticus is based on case reports with the reported indications in this group ranging from cardiovascular compromise, cardiac arrest, hypoxemia and shock, severe hypercap nia and acidosis, to dynamic hyperinflation [2, 6,7].…”
Section: Discussionmentioning
confidence: 99%
“…These data show that in patients treated with ECMO for status asthmaticus, hypercapnia, rather than hypoxemia, was the central exchange derangement, suggesting that a less invasive technique like ECCO 2 R will be suitable, with fewer complications. Although most of the clinical applications of ECCO 2 R for the treatment of obstructive lung diseases have been reported in patients with COPD, several cases describe ECCO 2 R in patients with near-fatal asthma [50][51][52][53][54] ( Table 4). The first cases reported were by using a pumpless extracorporeal life assist (pECLA) device.…”
Section: Severe Acute Asthmamentioning
confidence: 99%
“…Die Entwicklung erlaubt zudem ein Nachdenken darüber, bei Versagen der Atempumpe und NIV vor einer Intubation ein extrakorporales Unterstützungssystem einzusetzen. Bisher wurden in diesem Zusammenhang nur wenige Kasuistiken publiziert [41,42]. Solange keine ausreichende Evidenz für den frühen Einsatz der extrakorporalen Lungenunterstützungssysteme besteht und auch die Komplikationen noch nicht ausreichend untersucht sind, bleiben bei einem Versagen der Atempumpe die Verfahren der Beatmung über Maske und Tubus die Mittel der ersten Wahl.…”
Section: Extrakorporale Lungenunterstützungunclassified