Punctate exanthem of West Nile Virus infection: Report of 3 cases

Anderson, Robert C.; Horn, K; Hoang, Mai P.; Gottlieb, E; Bennin, Bruce

doi:10.1016/j.jaad.2004.05.031

Cited by 37 publications

(16 citation statements)

References 18 publications

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“…Consistent with previous reports, we found that ∼80% of patients in our series had maculopapular rash associated with WNV disease [8,13]. Although clinicians were not specifically asked to assess blanching, none described petechial rash.…”

supporting

confidence: 90%

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Characteristics of the Rash Associated with West Nile Virus Fever

Ferguson

Gershman

LeBailly³

et al. 2005

Clinical Infectious Diseases

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We characterized rash in 15 patients with West Nile virus (WNV) fever. Generalized, maculopapular rash typically occurred on days 5-12 of illness. Dysesthesia was reported by 27% of patients, and pruritus by 33% of patients. Because the rash was nonspecific and serologic test results were often negative for WNV at presentation, convalescent-phase testing was frequently required to diagnose WNV fever.

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supporting

confidence: 90%

“…To our knowledge, dysesthesias have not previously been reported with WNV-associated rash, and pruritic rash has only been described once [13].…”

mentioning

confidence: 84%

Characteristics of the Rash Associated with West Nile Virus Fever

Ferguson

Gershman

LeBailly³

et al. 2005

Clinical Infectious Diseases

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“…For example, hemorrhagic manifestations have been reported in a small number of patients with "neurotropic" viruses, such as Japanese encephalitis virus, St. Louis encephalitis virus, tick-borne encephalitis virus, and West Nile virus (WNV) (5,39,75,103,156). When the clinical spectrum is focused on just one virus, such as WNV, the broad spectrum becomes even more evident, since laboratory-confirmed WNV infections with additional atypical symptoms (such as hepatitis and pancreatitis) have been reported.…”

Section: Broad Spectrum Of the Clinical Manifestation Of Denguementioning

confidence: 99%

Emergence of the Severe Syndrome and Mortality Associated with Dengue and Dengue-Like Illness: Historical Records (1890 to 1950) and Their Compatibility with Current Hypotheses on the Shift of Disease Manifestation

Kuno

2009

Clin Microbiol Rev

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SUMMARY Outbreaks of the severe dengue syndrome, dengue hemorrhagic fever (DHF), emerged beginning in the 1950s, marking a dramatic change in the dengue syndrome. While intense investigations in multiple directions have been conducted for many years to elucidate the intrinsic mechanisms conducive to the development of DHF, no consensus has yet emerged. Meanwhile, relatively little attention has been paid to the occurrence of severe dengue and death prior to the 1950s. This comprehensive review was designed to evaluate outbreak records in the early dengue history to better understand the epidemiologic background and other factors that existed before the emergence of DHF outbreaks. By applying a set of stringent criteria to remove unreliable data as much as possible and by interpreting the results conservatively, a short list of etiologically more reliable outbreaks with high mortality was obtained. The results show that severe dengue syndrome, clinically very much compatible with DHF, occurred far more frequently in multiple locations than it had been assumed before; that the magnitudes of mortality in several outbreaks were not negligible; and that the epidemiologic background features shared among these outbreaks in the early period were, with the exceptions of more limited demographic changes, generally similar to the post-1950 conditions.

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“…Occasionally a transient rash may be noted ( Figure 2); this rash tends to be morbilliform, maculopapular, and non-pruritic, and predominates over the torso and extremities, sparing the palms and soles [66][67][68][69]. The rash may be very transient, lasting less than 24 hours in some persons.…”

Section: West Nile Fevermentioning

confidence: 99%

Manifestations of West Nile neuroinvasive disease

Sejvar

Marfin²

2006

Rev. Med. Virol.

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Since its introduction to North America in 1999, West Nile virus, an arthropod-borne flavivirus, has become the most significant cause of epidemic encephalitis in the western hemisphere. While most human infections with the virus are asymptomatic and the majority of symptomatic persons experience febrile illness, severe neurologic manifestations, including meningitis, encephalitis, and poliomyelitis may be seen. This review summarizes the virology, epidemiology and pathogenesis of human infection with West Nile virus, and details recent advances in our understanding of the pathophysiology and various clinical manifestations of infection.

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Punctate exanthem of West Nile Virus infection: Report of 3 cases

Cited by 37 publications

References 18 publications

Characteristics of the Rash Associated with West Nile Virus Fever

Characteristics of the Rash Associated with West Nile Virus Fever

Emergence of the Severe Syndrome and Mortality Associated with Dengue and Dengue-Like Illness: Historical Records (1890 to 1950) and Their Compatibility with Current Hypotheses on the Shift of Disease Manifestation

Manifestations of West Nile neuroinvasive disease

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