Punctate Inner Choroidopathy

Watzke, Robert C.; Packer, Andrew J.; Folk, James C.; Benson, William E.; Burgess, Dean B.; Ober, Richard R.

doi:10.1016/0002-9394(84)90243-5

Cited by 256 publications

(148 citation statements)

References 8 publications

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“…After follow-up for 12 months, the mean VA was maintained at 39 letters, which is far better than the natural history of the condition if untreated. 1,2 …”

Section: Discussionmentioning

confidence: 99%

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Photodynamic therapy combined with systemic corticosteroids for choroidal neovascularisation secondary to punctate inner choroidopathy

Fong

Thomas

Amin

et al. 2007

Eye

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Aim To report on visual acuity (VA) and angiographic outcomes in patients presenting with subfoveal choroidal neovascular membranes (CNV) secondary to punctate inner choroidopathy (PIC), treated with photodynamic therapy (PDT) with verteporfin combined with systemic corticosteroids. Methods A prospective case series of patients with subfoveal CNV secondary to PIC was analysed. All patients were treated with PDT combined with oral prednisolone (1 mg/kg body weight/day) which was started 5 days before PDT. Fluorescein angiography was performed at baseline and every 3 months post-treatment to establish the size, position, and activity of the CNV. Visual acuity was measured using the ETDRS scale. Further PDT treatment was carried out at follow-up visits if there was angiographic evidence of ongoing CNV activity. Results Five female patients with a mean age of 30.4 years (range 25-43 years) were treated over a 12-month period. The mean greatest linear diameter (GLD) of the CNV was 1.66 mm (range 0.46-3.28 mm). A mean improvement in vision of nine ETDRS letters (range À15-20 letters) after treatment was found, which was maintained at final followup. The mean follow-up time was 12 months (range 10-14 months). The mean number of PDT treatments was two (range 1-3). Conclusions: The vaso-occlusive effect of PDT combined with the vasostatic and antiinflammatory effect of systemic oral prednisolone appears to be a safe and effective option in the primary treatment of subfoveal CNV in patients with PIC.

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“…After follow-up for 12 months, the mean VA was maintained at 39 letters, which is far better than the natural history of the condition if untreated. 1,2 …”

Section: Discussionmentioning

confidence: 99%

“…1 Small yellow-white lesions at the level of the retinal pigment epithelium (RPE) are seen in the posterior pole and midperipheral retina, often bilaterally. Once inactive, these lesions leave pigmented punched out scars.…”

Section: Introductionmentioning

confidence: 99%

Photodynamic therapy combined with systemic corticosteroids for choroidal neovascularisation secondary to punctate inner choroidopathy

Fong

Thomas

Amin

et al. 2007

Eye

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“…Ampiginous choroiditis has been recently described as a clinical entity involving features of both acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and serpiginous choroiditis in relatively young patients, occurring predominantly in males It is a disease with multiple relapses which can be eff ectively controlled with a combination of immunosuppressive therapy and maintain a good visual acuity on long term follow-up. (Figure 4 a- 19 Lesions are bilateral, multiple, small, welldefi ned, yellow-white, usually 100-200 microns diameter and are limited to the posterior pole. Cells and fl are in the anterior chamber or vitreous cavity 20 are typically absent.…”

Section: Multifocal Choroiditis and Panuveitismentioning

confidence: 99%

White Dot Syndromes

Biswas¹

2015

DJO

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“…2 The symptoms are usually unilateral, but most patients show bilateral fundus involvement. 2,3 PIC is characterized by multifocal choroidal lesions (yellow-white lesions of the inner choroid and retinal pigment epithelium of approximately 100-300 μm in size), usually distributed throughout the posterior pole but sparing the peripapillary region. 2,4 There are no other signs of ocular inflammation elsewhere in the eye.…”

Section: Differential Diagnosismentioning

confidence: 99%