Pure cutaneous paratesticular leiomyosarcoma of the scrotum: A rare case report

Yagnik, Vipul D; Dawka, Sushil; Yagnik, Bhargav; Agnihotri, Arun Kumar; Agnihotri, Smriti

doi:10.4103/ua.ua_156_19

Cited by 2 publications

(3 citation statements)

References 7 publications

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“…Given the high survival rate, we can infer that an epididymectomy can provide good disease control. Previous case reports of paratesticular LMS also demonstrated good disease control with a simple tumorectomy [ 2 – 5 ].…”

Section: Discussionmentioning

confidence: 83%

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Management of epididymal leiomyosarcoma: literature narrative, case report and discussion on the use of simple epididymectomy or high radical orchiectomy

Tchienga

Banayan

Arulin

et al. 2023

Journal of Surgical Case Reports

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Section: Discussionmentioning

confidence: 83%

“…Though curative, it can impair patients’ sexual lives. Simple tumorectomies have less sexual dysfunction and can provide good disease control [ 2 – 5 ]. This paper discusses when to use a simple epididymectomy or a high-radical orchiectomy for managing epididymal tumors.…”

Section: Introductionmentioning

confidence: 99%

Management of epididymal leiomyosarcoma: literature narrative, case report and discussion on the use of simple epididymectomy or high radical orchiectomy

Tchienga

Banayan

Arulin

et al. 2023

Journal of Surgical Case Reports

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“…On the other hand, testis-sparing surgery has recently attracted attention as a less-invasive treatment option for paratesticular STS [ 14 – 16 ]. Previous case reports of paratesticular LMS demonstrated good disease control even when treated by simple tumorectomy sparing the testis [ 5 , 6 , 17 , 18 ]. However, the prognostic factors and optimal treatment strategy for paratesticular LMS remain unclear because of its rarity.…”

Section: Introductionmentioning

confidence: 99%

Optimal surgical treatment for paratesticular leiomyosarcoma: retrospective analysis of 217 reported cases

et al. 2022

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Background Paratesticular leiomyosarcoma (LMS) is a rare tumor. Conventionally, tumor resection by high inguinal orchiectomy is performed as the preferred treatment approach for paratesticular sarcoma. On the other hand, testis-sparing surgery has recently attracted attention as a less-invasive treatment option for paratesticular sarcoma. However, the prognostic predictors and optimal treatment strategy for paratesticular LMS remain unclear because of its rarity. In this study, we systematically reviewed previously reported cases of paratesticular LMS to evaluate the prognostic factors and establish the optimal treatment strategy. Methods A systematic search of Medline, Web of Science, Embase, and Google was performed to find articles describing localized paratesticular LMS published between 1971 and 2020 in English. The final cohort included 217 patients in 167 articles. The starting point of this study was the time of definitive surgical treatment, and the end point was the time of local recurrence (LR), distant metastasis (DM), and disease-specific mortality. Results Patients with cutaneous LMS had a slightly better LR-free survival, DM-free survival, and disease-specific survival than those with subcutaneous LMS (p = 0.745, p = 0.033, and p = 0.126, respectively). Patients with higher grade tumors had a significantly higher risk of DM and disease-specific mortality (Grade 3 vs Grade 1 p < 0.001, and Grade 3 vs Grade 1 p < 0.001, respectively). In addition, those with a microscopic positive margin had a significantly higher risk of LR and DM than those with a negative margin (p < 0.001, and p = 0.018, respectively). Patients who underwent simple tumorectomy had a slightly higher risk of LR than those who underwent high inguinal orchiectomy (p = 0.067). Subgroup analysis of cutaneous LMS demonstrated that the difference in LR between simple tumorectomy and high inguinal orchiectomy was limited (p = 0.212). On the other hand, subgroup analysis of subcutaneous LMS revealed a significant difference in LR (p = 0.039). Conclusions Our study demonstrated that subcutaneous LMS and high-grade tumors are prognostic factors for paratesticular LMS. For subcutaneous LMS, tumorectomy with high inguinal orchiectomy should be the optimal treatment strategy to achieve a negative surgical margin.

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Pure cutaneous paratesticular leiomyosarcoma of the scrotum: A rare case report

Cited by 2 publications

References 7 publications

Management of epididymal leiomyosarcoma: literature narrative, case report and discussion on the use of simple epididymectomy or high radical orchiectomy

Management of epididymal leiomyosarcoma: literature narrative, case report and discussion on the use of simple epididymectomy or high radical orchiectomy

Optimal surgical treatment for paratesticular leiomyosarcoma: retrospective analysis of 217 reported cases

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