Pure red cell aplasia associated with type I autoimmune polyglandular syndrome—successful response to treatment with mycophenolate mofetil: case report and review of literature

A child with autoimmune polyendocrinopathy candidiasis and ectodermal dysplasia treated with immunosuppression: a case report

“…Immunosuppression was unsuccessful with azathioprine but successful with cyclosporin A [7]. A patient with APECED with pure red cell aplasia responding well to MMF has also been described [8]. …”

Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy

“…The AD Addison's disease, AIH Autoimmune hepatitis, Az azathioprine, CyA Cyclosporine A, GID gastrointestinal dysfunction, ILD interstitial lung disease, MMF mycophenolate mofetil, OF ovarian failure, TIN Tubulo-interstitial nephritis a the same patient at 2, 7, 12 and 13 years of age reactivation of CMC does not seem to be a major problem; however, prophylactic antimicrobial treatment could be provided during aggressive immunosuppression [101]. Keratoconjunctivitis and alopecia have improved during cyclosporine A treatment, but adrenocortical and ovarian failure still progressed, as did exocrine pancreatitis, thyroiditis and thrombocytopenia during MMF treatment [110,122,156]. TIN is another serious manifestation that has developed during Sirolimus treatment [101].…”

Large granular lymphocytic leukemia complicating autoimmune polyglandular syndrome type 1 in siblings

“…Orlova and colleagues recently reviewed this literature, following their experience with a 26‐year‐old woman with APS1 who developed pure red cell aplasia responsive to mycophenolic acid . Prior reports of pure red cell aplasia in the setting of APS1 have not described siblings with pure red cell aplasia complicating the course of more than one family member . Of the cases reported to date, no siblings have been described previously.…”