Purification and Characterization of d-Lyxose Isomerase

The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings

“…In this disorder, high concentrations of the C5 sugars, ribose and arabinofuranose, and of C5 polyols arabitol and xylitol and C4 threitol were found in body fluids [32]. Arabitol and xylitol are keymetabolites of the ''Pentose and Glucuronate interconversion'' pathway: they may come from lyxose, another dietary C5 sugar, through a gut-bacterial isomerase [33].…”

Untitled

“…The substrates of D-lyxose isomerase are D-lyxose and D-mannose [2,3] and the enzyme catalyzes the first reaction in the metabolism of both sugars [4]. D-Ribose isomerase is the first enzyme of the metabolism of D-ribose and was induced by D-ribose, and D-lyxose isomerase also was induced by Dribose gratuitously [5,6].…”

Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp.

“…To date only a small number of LI enzymes have been characterized including those from Aerobacter aerogenes (Anderson and Allison, 1965), Cohnella laevoribosii (Cho et al, 2007a), Serratia proteamaculans (Park et al, 2010), Escherichia coli (van Staalduinen et al, 2010), Providancie stuartii (Kwon et al, 2010), Bacillus licheniformis (Patel et al, 2011), Bacillus subtilis (Marles-Wright and Lewis, 2011), Dictyoglomus turgidum (Choi et al, 2012) and Thermosediminibacter oceani (Yu et al, 2016).…”