Purification and properties of the melanization and reddish colouration hormone (MRCH) in the armyworm, Leucania separata (Lepidoptera)

Matsumoto, Shogo; Isogai, Akira; Suzuki, Akira; Ogura, Nobuo; Sonobe, Haruyuki

doi:10.1016/0020-1790(81)90065-2

Cited by 50 publications

(19 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specific phenotypic effects on pigmentation, wing shape, catecholamine pools, and photonegativity all may reflect different alterations in neuropeptide processing, although it is not yet possible to specify any particular causal relationships. It is tempting to speculate that defects in processing a Drosophila homolog of neuropeptides controlling melanization, such as those found in other insects (38,39), might be responsible for the reduced pigmentation seen in svr mutant flies. However, neither the identity nor the role of melanizing hormones in Drosophila has been established.…”

Section: Discussionmentioning

confidence: 99%

The silver gene of Drosophila melanogaster encodes multiple carboxypeptidases similar to mammalian prohormone-processing enzymes.

Settle

Green

Burtis

1995

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

The silver (svr) gene of Drosophila melanogaster is required for viability, and severe mutant alleles result in death prior to eclosion. Adult flies homozygous or hemizygous for weaker alleles display several visible phenotypes, including cuticular structures that are pale and silvery in color due to reduced melanization. We have identified and cloned the DNA encoding the svr gene and determined the sequence of several partially overlapping cDNAs derived from svr inRNAs. The predicted amino acid sequence of the polypeptides encoded by these cDNAs indicates that the silver proteins are members of the family of preprotein-processing carboxypeptidases that includes the human carboxypeptidases E, M, and N. One class of svr mRNAs is alternatively spliced to encode at least two polyproteins, each of which is composed of two carboxypeptidase domains.

show abstract

Section: Discussionmentioning

confidence: 99%

The silver gene of Drosophila melanogaster encodes multiple carboxypeptidases similar to mammalian prohormone-processing enzymes.

Settle

Green

Burtis

1995

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

show abstract

“…MRCH-rI~ Since minute amounts of purified MRCH-III were obtained (40 pmol)s it was subjected to failed to inactivate MRCH as previously reported [6].…”

Section: N-terminal Amino Acid Sequence Ofmentioning

confidence: 99%

N‐terminal amino acid sequence of an insect neurohormone, melanization and reddish coloration hormone (MRCH): heterogeneity and sequence homology with human insulin‐like growth factor II

1985

Self Cite

View full text Add to dashboard Cite

An insect neurohormone, metanization and reddish coloration hormone (MRCH), is responsible for cuticular melanization and epidermal red pigmentation in the armyworm, The three molecular forms of MRCH were isolated from adult heads of the silkworm, Bombyx mori, and their N-terminal amino acid sequences revealed a sequence homolgy with the C-terminal region of human insulin-like growth factor-II as well as N-terminal heterogeneity of MRCHs.

show abstract

“…The purification procedure for EH through steps 1 to 10 was the same as for prothoracicotropic hormone (PTTH) described previously7 --9): EH activity was separated from melanization and reddish colouration hormone (MRCH) at step 2 10 ) and from PTTH at step 10.…”

Section: ) Purification Of Ehmentioning

confidence: 99%

Purification and Properties of Eclosion Hormone of the Silkworm,Bombyx mori

Nagasawa

Fugo

Takahashi

et al. 1983

Agricultural and Biological Chemistry

Self Cite

View full text Add to dashboard Cite

Purification and properties of the melanization and reddish colouration hormone (MRCH) in the armyworm, Leucania separata (Lepidoptera)

Cited by 50 publications

References 24 publications

The silver gene of Drosophila melanogaster encodes multiple carboxypeptidases similar to mammalian prohormone-processing enzymes.

The silver gene of Drosophila melanogaster encodes multiple carboxypeptidases similar to mammalian prohormone-processing enzymes.

N‐terminal amino acid sequence of an insect neurohormone, melanization and reddish coloration hormone (MRCH): heterogeneity and sequence homology with human insulin‐like growth factor II

Purification and Properties of Eclosion Hormone of the Silkworm,Bombyx mori

Contact Info

Product

Resources

About