Purification and Some Properties of Five Distinct Acyl-Coa Dehydrogenases From Bovine Liver

Abstract

Acyl-CoA dehydrogenases have gained considerable interest in the past few years. This was due to a large extent to the discovery of genetic defects in the B-oxidation cycle and their connection with the "sudden infant death syndrome" (SIDS) [I]. Up to date, several cases of genetic defects involving a-B-dehydrogenation and in particular the enzyme medium chain acyl-CoA dehydrogenase have been reported [2,3].The occurrence of such defects involving the short chain-and long chain acyl-CoA dehydrogenases is more limited.