Purification, Characterization and Bioactivities of Polysaccharides Extracted from Safflower (Carthamus tinctorius L.)

Abstract

Polysaccharides are the main bioactive components in safflower. In this study, safflower polysaccharides (SPs) were extracted by ultrasonic assisted extraction, and four purified safflower polysaccharide fractions (named SSP1, SSP2, SSP3, and SSP4, respectively) were obtained. The physicochemical properties and in vitro physiological activities of the four fractions were investigated. The molecular weights (MW) of the SSPs were 38.03 kDa, 43.17 kDa, 54.49 kDa, and 76.92 kDa, respectively. Glucuronic acid, galactose acid, glucose, galactose, and arabinose were the main monosaccharides. The Fourier transform infrared spectroscopy (FT-IR) indicated that the polysaccharides had α- and β-glycosidic bonds. Nuclear magnetic resonance (NMR) analysis showed that SSP1 had 6 different types of glycosidic bonds, while SSP3 had 8 different types. SSP3 exhibited relatively higher ABTS+ scavenging activity, Fe+3-reduction activity, and antiproliferative activity. The results will offer a theoretical framework for the use of SPs in the industry of functional foods and medications.

The Encapsulation of Natural Organic Dyes on TiO2 for Photochromism Control

“…In this study, we propose an effective strategy that exploits the encapsulation of natural organic dyes on TiO 2 particles and creates warm tone colored materials with (1) violet, (2) orange, and (3) yellow, ultimately preserving the photochromism. We demonstrate that introducing three different natural organic dyes, including (1) purpurin (1,2,4-Trihydroxyanthraquinone) [34], (2) curcumin (Curcuma longa), and (3) safflower (Carthamus tinctorius) [35], effectively mitigates photochromism and increases the dispersing ability of TiO 2 in the fabrication process of color paste. The introduction of natural organic dyes increases the diameter of TiO 2 hybrid particulates with increasing concentrations aided by their outstanding adsorption and penetration.…”

Genetic diversity, clinical uses, and phytochemical and pharmacological properties of safflower (Carthamus tinctorius L.): an important medicinal plant

“…PBPC, a polysaccharide extracted from safflower bee pollen, has attracted the attention of the scientific community owing to its unique origin and biological activity (Wu et al, 2021). Four purified safflower polysaccharide fractions (named SSP1, SSP2, SSP3, and SSP4, respectively) were extracted from safflower by ultrasonic assisted extraction, among which SSP3 exhibited relatively higher antiproliferative activity, Fe +3 -reduction activity, and ABTS+ scavenging activity (Wang et al, 2023b).…”

Single‐Cell Sequencing Reveals MYOF‐Enriched Monocyte/Macrophage Subcluster as a Favorable Prognostic Factor in Sepsis

“…[9] However, this binary M1/M2 classification is increasingly viewed as an oversimplification and is insufficient to capture the nuanced roles and heterogeneity of macrophages in sepsis. [10,11] Emerging evidence suggests that macrophages can polarize into a spectrum of functional states, influenced by their microenvironment. [12,13] This cellular heterogeneity may contribute to the complexity and variability in sepsis outcomes.…”