2007
DOI: 10.1016/j.molcel.2007.05.007
|View full text |Cite
|
Sign up to set email alerts
|

Purification of a Plant Mediator from Arabidopsis thaliana Identifies PFT1 as the Med25 Subunit

Abstract: Mediator, a central coregulator of transcription, has been identified as a large protein complex in eukaryotes ranging from yeast to man. It is therefore remarkable that Mediator has not yet been identified within the plant kingdom. Here we identify Mediator in a plant, Arabidopsis thaliana. The plant Mediator subunits typically show very low homology to other species, but our biochemical purification identifies 21 conserved and six A. thaliana-specific Mediator subunits. Most notably, we identify the A. thali… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4

Citation Types

5
348
2
1

Year Published

2010
2010
2023
2023

Publication Types

Select...
3
3

Relationship

0
6

Authors

Journals

citations
Cited by 272 publications
(356 citation statements)
references
References 60 publications
5
348
2
1
Order By: Relevance
“…2). These include more paralogs for six Meds (Med15, as well as orthologs for Med26, Med30, and the kinase module subunits not identified earlier in the biochemical screen (Bäckströ m et al, 2007). We have identified SENSITIVE TO FREEZING6 (SFR6) as Med16, a nucleus-localized protein with roles in cold acclimation (Knight et al, 2009) as well as photoperiodic and clock gene expression (Knight et al, 2008).…”
Section: Identification Of Med Proteins In Plantsmentioning
confidence: 99%
See 4 more Smart Citations
“…2). These include more paralogs for six Meds (Med15, as well as orthologs for Med26, Med30, and the kinase module subunits not identified earlier in the biochemical screen (Bäckströ m et al, 2007). We have identified SENSITIVE TO FREEZING6 (SFR6) as Med16, a nucleus-localized protein with roles in cold acclimation (Knight et al, 2009) as well as photoperiodic and clock gene expression (Knight et al, 2008).…”
Section: Identification Of Med Proteins In Plantsmentioning
confidence: 99%
“…Med subunits have been biochemically identified in several fungi and metazoans but only for one plant, Arabidopsis (Bäckströ m et al, 2007). In this study, putative Meds have been identified in seven groups of the plant kingdom by Hidden Markov Model (HMM) methods.…”
Section: Identification Of Med Proteins In Plantsmentioning
confidence: 99%
See 3 more Smart Citations