Purple Urine Bag Syndrome- An Alarming Situation

Faridi, Mohammad Shazib; Mj, Rahman; Mibang, Naloh; Shantajit, N; Somarendra, Khumukchum

doi:10.7860/jcdr/2016/16622.7209

Cited by 7 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aside from the sulphatase and phosphatase-producing bacteria, some predisposing factors must be present to develop PUBS. 6,13 Patients with long-term urinary catheter usage, constipation, dementia, alkaline urine, dehydration, and female gender are at risk of developing PUBS. 4,13,14 A high bacterial load in the urine combined with these factors facilitates the development of PUBS and increases the availability of bacterial sulphatases and phosphatases.…”

Section: Discussionmentioning

confidence: 99%

“…4,5 Notably, while the vivid discoloration is benign, it acts as a visual cue for clinicians as the most common clinical presentation. 6 Although the appearance of PUBS is benign, it can serve as a disconcerting sight for family members and caregivers alike. For medical professionals, the emergence of PUBS indicates an underlying red flag, often pointing toward a UTI that may have arisen due to lapses in the maintenance or hygiene of the urinary catheter.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Peculiar Manifestation of Urinary Tract Infection in a 76-year-old Female

Alius Cahyadi,

Angelina Yuwono,

Nicholas Adrianto

et al. 2023

IJTID

View full text Add to dashboard Cite

Purple Urine Bag Syndrome (PUBS) is a rare and benign clinical phenomenon associated with urinary tract infections, characterized by the distinctive purple discoloration of a urinary catheter bag. The underlying cause of PUBS is related to bacterial activity involved in the breakdown of tryptophan, mainly in individuals with predisposing factors such as long-term catheterization, constipation, alkaline urine, and being female. We present the case of a 76-year-old female patient with a history of tuberculous spondylitis who developed PUBS during her hospital stay. The patient had been bedridden for three years and had been given a urinary catheter, which was routinely replaced by a non-medical family member and without a proper antiseptic procedure. A urine culture revealed the presence of Proteus mirabilis, and the patient was treated with intravenous antibiotics while also replacing the urinary catheter and bag. After five days of treatment, the urine bag and catheter remained clear, and the patient was discharged. PUBS is a significant indicator of urinary tract infection, necessitating prompt medical intervention to prevent complications. Healthcare professionals should be aware of this syndrome to enable early detection and appropriate management.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Peculiar Manifestation of Urinary Tract Infection in a 76-year-old Female

Alius Cahyadi,

Angelina Yuwono,

Nicholas Adrianto

et al. 2023

IJTID

View full text Add to dashboard Cite

show abstract

“…Risk factors are advanced age, female gender, chronic coagulation and permanent catheterization of the urinary tract, as well as dementia, presence of alkaline urine and recurrent UTI. It is also frequent in institutionalized patients [5,6].…”

Section: Discussionmentioning

confidence: 99%

Purple urine bag syndrome

Duarte-Arzuaga¹,

González-Rodríguez²

2020

Arch Urol Res

View full text Add to dashboard Cite

Purple Urine Bag Syndrome (PUBS) is an unusual occurrence characterized by the purple coloration of the urine. It is observed in bedridden patients with multiple comorbidities, urinary catheters and subjacent urinary infections by germs including Escherichia coli and Morganella morganii. It is caused by the action of sulfatase and phosphatase-producing bacteria which produce compounds that cross-react with chemicals in urine collection bags, rendering the purple coloration. The objective of the article is to disseminate knowledge about PUBS, which is rare and alarming for the patient and their relatives. We present a case of an 87-year-old patient, bedridden, with recurrent urinary tract infection due to E. coli and Klebsiella pneumoniae, and prolonged urethral catheterization who presented purple urine during admission. The specifi c antibiotic treatment together with the change of the urinary catheter and the bag managed to rinse the urine.

show abstract

“…It slows gut motility and changes intestinal bacterial flora. Bowel bacterial flora containing tryptophanase convert dietary tryptophan to indole, pyruvic acid, and ammonia 3–5 , 8 , 10 . Indole is absorbed and enters the liver via the portal circulation.…”

Section: Discussionmentioning

confidence: 99%

“…It occurs when a decrease in bowel motility causes bacterial overgrowth in the intestine, leading to increased metabolism of tryptophan to indole, resulting in high levels of indigo and indirubin in the urine 3–11 . The majority of PUBS patients are bed ridden, primarily female, with an indwelling urinary catheter, experiencing constipation and a UTI with a urine alkaline pH 3–5 , 8–12 . Most studies have reported that PUBS is benign, harmless, and even asymptomatic 3 , 4 , 7 , 13 .…”

Section: Introductionmentioning

confidence: 99%

Risk factors of mortality in patients with purple urine bag syndrome

Yang

2019

Journal of Drug Assessment

View full text Add to dashboard Cite

Aim: Purple urine bag syndrome (PUBS) is rarely seen in clinical practice. Several studies have reported that PUBS is relatively benign in its clinical course, but this study aimed to identify risk factors for mortality related to PUBS. Materials and methods: In a PubMed search from October 1980 to August 2016, using the search term “Purple urine bag syndrome (PUBS)”, 106 articles (n = 174 cases) were identified. This study excluded 58 cases. Among them, 14 cases did not include information on patient sex and four cases did not include information on patient age. Thirty-seven cases did not report the white blood cell (WBC) count, shock, fever, or etiology. Three cases did not report patient survival. This study considered 116 PUBS cases. Chi-square tests were used to compare the survival and mortality groups. Results: In relative risk analysis, uremia (17.8), shock (14.4), diabetes (4.8), leukocytosis (1.1), and female sex (1.1) were significant risk factors for mortality after PUBS. However, it is possible that PUBS cases are under-reported worldwide. Conclusions: PUBS is a warning sign of a urinary tract infection, and it often follows a relatively benign clinical course. This study found that female sex, leukocytosis, shock at presentation, comorbidity with diabetes, and uremia are risk factors for mortality associated with PUBS.

show abstract

Purple Urine Bag Syndrome- An Alarming Situation

Cited by 7 publications

References 6 publications

A Peculiar Manifestation of Urinary Tract Infection in a 76-year-old Female

A Peculiar Manifestation of Urinary Tract Infection in a 76-year-old Female

Purple urine bag syndrome

Risk factors of mortality in patients with purple urine bag syndrome

Contact Info

Product

Resources

About