Purpura Fulminans in Infantile Streptococcal Septicemia

Piparsania, Saurabh; Rajput, Nitin; Singh, Kunal; Zade, Priti; Joshi, Medha

doi:10.4236/ss.2011.210109

Cited by 2 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PF is generally associated with poor outcome as observed in other reports [2,15,16]. The second case survived against a lot of odds inspite of the initial protracted shock and multi-organ dysfunction with the lack of intensive care.…”

Section: Discussionsupporting

confidence: 54%

Purpura Fulminans with Peripheral Gangrene in Severe Falciparum Malaria: A Case Series

Fowotade¹,

Re²,

Oe³

et al. 2018

View full text Add to dashboard Cite

Background: Purpura fulminans is an acute fatal illness consisting of septicaemia, shock, and disseminated intravascular coagulation, often manifesting with gangrene of the distal extremities and necrosis of skin. Purpura fulminans associated with severe malaria has rarely been reported among children. Case Report: Two cases of purpura fulminans with disseminated intravascular coagulation probably due to severe falciparum malaria, are presented from a tertiary health facility in Nigeria. Both cases were males, and were infants aged 6 and 7 months respectively. They presented with fever, seizures, loss of consciousness and features of shock and had associated peripheral gangrene which developed hours into admission. Investigations showed P. falciparum hyper-parasitemia and evidence of disseminated intravascular coagulation. No focus for sepsis was identified and there were no bacterial isolates from blood culture. The second child survived but was left with amputated digits and audiovisual deficits. Conclusion: The cases presented demonstrate that purpura fulminans can occur in children with severe malaria even in P. falciparum endemic settings.

show abstract

Section: Discussionsupporting

confidence: 54%

Purpura Fulminans with Peripheral Gangrene in Severe Falciparum Malaria: A Case Series

Fowotade¹,

Re²,

Oe³

et al. 2018

View full text Add to dashboard Cite

show abstract

“…DIC triggers systemic activation of blood coagulation resulting in excessive blood clotting, which leads to endothelial injury. As the condition progresses, clotting factors and platelets are consumed in widespread intravascular coagulation, which can result in severe bleeding (9). Although bacteria such as Neisseria meningitidis and Streptococcus pneumoniae are the most common microorganisms that cause PF, viruses can rarely cause it (10).…”

Section: Discussionmentioning

confidence: 99%

Association of COVID-19 Infection and Purpura Fulminans

Dashti¹,

Dehghani

Moravej

et al. 2021

Arch Pediatr Infect Dis

View full text Add to dashboard Cite

: Coronavirus disease 2019 (COVID-19) was officially declared as a pandemic on March 11, 2020. Although most patients with COVID-19 manifest fever and respiratory tract symptoms, extrapulmonary and atypical presentations, such as gastrointestinal, neurologic, and cardiovascular involvement as well as thromboembolic events have been reported amongst COVID-19 patients. Herein, we aim to describe a COVID-19 patient who progressed to purpura fulminans.

show abstract

Purpura Fulminans in Infantile Streptococcal Septicemia

Cited by 2 publications

References 4 publications

Purpura Fulminans with Peripheral Gangrene in Severe Falciparum Malaria: A Case Series

Purpura Fulminans with Peripheral Gangrene in Severe Falciparum Malaria: A Case Series

Association of COVID-19 Infection and Purpura Fulminans

Contact Info

Product

Resources

About