2019
DOI: 10.3923/pjbs.2019.537.544
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Purslane and Garden Cress Seeds as Source of Unconventional Edible Oils for Prevention of Hyperlipidemia

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Cited by 8 publications
(6 citation statements)
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“…The results for daily food intake, spleen weight, and fats associated with heart, liver, kidney, and spleen were significant for safety trials, whereas weight gain, FER, liver weight, heart, and liver fats were significant for the treatment trial. This decreased food intake might have been linked with the higher fiber content of GCSs, resulting in increased satiety and lowered body weight and fat deposits in the body as it has been identified in some previous studies by Mohamed et al (2019) and Slavin (2005). Furthermore, Ω‐3 PUFAs intake has been linked with these appetite‐suppressing effects, adipocyte apoptosis, and changes in gene expression in skeletal muscle, heart, liver, and adipose tissues that suppress fat formation and promote fat oxidation and energy expenditure may all contribute to the reported body fat decreases (Buckley & Howe, 2009).…”
Section: Resultsmentioning
confidence: 73%
See 1 more Smart Citation
“…The results for daily food intake, spleen weight, and fats associated with heart, liver, kidney, and spleen were significant for safety trials, whereas weight gain, FER, liver weight, heart, and liver fats were significant for the treatment trial. This decreased food intake might have been linked with the higher fiber content of GCSs, resulting in increased satiety and lowered body weight and fat deposits in the body as it has been identified in some previous studies by Mohamed et al (2019) and Slavin (2005). Furthermore, Ω‐3 PUFAs intake has been linked with these appetite‐suppressing effects, adipocyte apoptosis, and changes in gene expression in skeletal muscle, heart, liver, and adipose tissues that suppress fat formation and promote fat oxidation and energy expenditure may all contribute to the reported body fat decreases (Buckley & Howe, 2009).…”
Section: Resultsmentioning
confidence: 73%
“…Lowering blood glucose and restoring other biochemical parameters by GC have been previously reported by Attia et al (2019). Similarly, hypoglycemic, hypolipidemic, and liver‐protective activity of GCSs were found comparable to a medicinal dose of atorvastatin (Amawi & Aljamal, 2012; Hikal, 2017; Mohamed et al, 2019; Prajapati et al, 2018; Salama et al, 2019).…”
Section: Resultsmentioning
confidence: 90%
“…However, this causes the liver to receive an increased amount of free fatty acids, which eventually stimulates the creation of TGs and cholesterol (in particular LDL-c), thus resulting in dyslipidemia ( Mourrieras et al, 1997 , Aldayel et al, 2020 ). Additionally, hyperglycemia alone is an independent factor that stimulates CHOL and TGs creation in the liver by upregulating the sterol regulatory element-binding transcription factors (SREB1/2) and their downstream fat synthesis genes ( Matsuzaka et al, 2004 , Mohamed et al, 2019 ). Previous investigates have shown higher levels of TGs, FFAs, LDL-c, VLDL-c, and CHOL, a significant decrease in the serum and liver levels, and increased TG and CHOL deposition in the STZ-diabetic rat kidneys ( Almeida et al, 2012 , Okoduwa et al, 2017 , Chen et al, 2019 , Aldayel et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…Anusha et al [53] found that aqueous extract of purslane in combination with lycopene showed hepatoprotective results against carbon tetrachloride induced hepatotoxicity in rats. The seeds of purslane are very effective against nonalcoholic fatty liver disease which is the most common form of chronic liver disease [233,234]. The gastro and hepatoprotective properties of purslane also suggest its use in the treatment of lung and liver related diseases.…”
Section: Gastro and Hepatoprotective Potentialmentioning
confidence: 99%