Pustular dermatosis (Sneddon—Wilkinson disease): case study

Raznatovskiy, K. I.; Piryatinskaya, V. A.; Karyakina, L. A.; Smirnova, O. N.; Lalaeva, A M; Vinnichuk, S. A.; Khabbus, A. G.

doi:10.17116/klinderma201716336-39

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…In isolated cases, the method of indirect FIR reveals circulating antibodies to IgA directed against epidermal cells. According to the modern classi ication, such cases are described as the SPD type of pemphigus [9]. Differential diagnosis is presented in the (Table 1).…”

Section: Introductionmentioning

confidence: 99%

Subcorneal pustular dermatosis (Sneddon-Wilkinson disease): a case report

Potekaev¹,

Morozova²,

Bobko³

et al. 2023

Ann Dermatol Res

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This article contains modern data on the etiology, clinical presentation and treatment as well as the differential diagnosis of a rare dermatosis, Sneddon-Wilkinson disease. Clinical observation of subcorneal pustular dermatosis in a 68-year-old woman is reported. Histopathological examination played a key role in making the correct diagnosis. Treatment consisted of a physiotherapeutic approach (311 nm UVB phototherapy) in combination with systemic glucocorticosteroids (dexamethasone). This therapeutic approach (instead of dapsone therapy) can be used due to its relatively good safety profile.

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Section: Introductionmentioning

confidence: 99%

Subcorneal pustular dermatosis (Sneddon-Wilkinson disease): a case report

Potekaev¹,

Morozova²,

Bobko³

et al. 2023

Ann Dermatol Res

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Features of clinical diagnosis of IgA-pemphigus in a patient with a long history of the disease

Sorokina

Krinitsyna

Pakhomova

2023

Russian Journal of Skin and Venereal Diseases

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Ige-dependent pemphigus is a rare autoimmune vesicular disease and is characterized by painful and itchy vesicular rashes on the skin. Ige-dependent pemphigus is one of the rarest forms of autoimmune bullous dermatoses. The article describes the clinical case of patient T., aged 82 y.o., who applied to the Novosibirsk Regional Clinical Dermatovenerologic Dispensary with complaints of rashes on the skin of the trunk, limbs, periodically accompanied by itching. For the first time, rashes began to appear 20 years ago, more often in the summer. She was observed by a rheumatologist with a diagnosis of chronic vasculitis, during exacerbation, against the background of therapy with systemic glucocorticosteroids, the rashes regressed. During the last exacerbation after suffering a Novel coronavirus infection at the age of 82 y.о., patient turned to a dermatologist against the background of an injection of a solution with betamethasone, with partially regressed rashes, which made it difficult to establish a diagnosis. After 2 weeks, against the background of discontinuation of therapy, another exacerbation occurred, characterized by obvious clinical manifestations of neutrophilic bullous dermatosis in the form of flaccid pustulеs on the skin of the trunk, upper extremities, as well as serous-purulent crusts arranged in the form of rings and garlands. Based on the history, clinical features and laboratory studies, without the use of immunofluorescence, a provisional diagnosis of IgA-dependent pemphigus was made, systemic glucocorticoid therapy was prescribed with a long-term gradual withdrawal, with a positive effect.

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Pustular dermatosis (Sneddon—Wilkinson disease): case study

Cited by 2 publications

References 7 publications

Subcorneal pustular dermatosis (Sneddon-Wilkinson disease): a case report

Subcorneal pustular dermatosis (Sneddon-Wilkinson disease): a case report

Features of clinical diagnosis of IgA-pemphigus in a patient with a long history of the disease

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