2018
DOI: 10.1016/j.micpath.2018.06.003
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Putative type II toxin-antitoxin systems in Listeria monocytogenes isolated from clinical, food, and animal samples in Iran

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Cited by 31 publications
(21 citation statements)
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“…Similarly, lipid metabolism is important for intracellular life cycle, for example, to make use of host lipids as energy sources and to modulate host immune responses (65). Recent studies found existence of several type II toxin-antitoxin systems in L. monocytogenes connected to stress conditions (66,67), though their role in virulence needs further investigation. Two competence genes (lmo2189 and lmo1397) were positively correlated, while one (lmo1346) was negatively correlated to virulence level.…”
Section: Figmentioning
confidence: 99%
“…Similarly, lipid metabolism is important for intracellular life cycle, for example, to make use of host lipids as energy sources and to modulate host immune responses (65). Recent studies found existence of several type II toxin-antitoxin systems in L. monocytogenes connected to stress conditions (66,67), though their role in virulence needs further investigation. Two competence genes (lmo2189 and lmo1397) were positively correlated, while one (lmo1346) was negatively correlated to virulence level.…”
Section: Figmentioning
confidence: 99%
“…L. monocytogenes causes human listeriosis, a rare disease associated with high rates of hospitalization and mortality [6,7]. The infection is mainly linked to the consumption of contaminated ready-to-eat foods, such as cheese and other dairy products, processed meats, salads, seafood, and raw eggs [8,9]. Another bacterium, S. aureus, which belongs to the Gram-positive Micrococcaceae family, is considered to be one of the most common causes of foodborne disease in the world [10].…”
Section: Introductionmentioning
confidence: 99%
“…The following TAS pairs were identified mainly using in silico methods in the strain ATCC19117 (with their corresponding gene names in L. monocytogenes EGD-e): lmo0113-0114, lmo0887-0888, and lmo1301-1302, predicting their 3D structure and potential inhibitory peptides. This report also showed by qPCR that lmo0113 is upregulated upon heat stress [21,22]. Another report investigated the TAS lmo0887-888 of L. monocytogenes EGD-e in more detail, ruling out the classical MazF action, but without demonstrating the exact role of this TAS in L. monocytogenes [20].…”
Section: Introductionmentioning
confidence: 79%
“…In silico predictions using TADB2 reveal only two TASs in L. monocytogenes EGD-e: lmo0113-0114 and lmo0887-0888 [19]. There are a few studies investigating TAS systems in L. monocytogenes [20][21][22] focusing only on a few L. monocytogenes strains and a few TAS pairs. The following TAS pairs were identified mainly using in silico methods in the strain ATCC19117 (with their corresponding gene names in L. monocytogenes EGD-e): lmo0113-0114, lmo0887-0888, and lmo1301-1302, predicting their 3D structure and potential inhibitory peptides.…”
Section: Introductionmentioning
confidence: 99%