“…78,87,102,103 An increased risk of SCC has been convincingly demonstrated for psoriasis patients treated with psoralen and ultraviolet A (PUVA). 80,[103][104][105] Treatment with either coal-tar or cyclosporine also increases the risk of SCC development. 80,106,107 Although numerous studies fail to demonstrate an increased risk of melanoma among PUVA-treated psoriasis patients, 80,83,87,91 one group found an increased risk of melanoma among psoriasis patients treated with aggressive PUVA after fifteen years of follow-up.…”