PUVA-bath photochemotherapy for congenital palmoplantar keratoderma in an 11-year-old girl

Phototherapy and photochemotherapy in childhood dermatoses

“…Jain et al [34] treated 20 patients with psoriasis (plaque psoriasis 18, guttate psoriasis 2) aged between 6 and 14 years with NBUVB. In a twice-weekly treatment regimen, the mean cumulative dose required for clearance was 4286 mJ/cm 2 (1,687-7,509 mJ/cm 2 ) over a mean number of treatment sessions of 24 (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30). The highest dose per treatment was 329 mJ/cm 2 (165-462 mJ/cm 2 ).…”

“…Mycosis fungoides (topical PUVA) [17] Lymphomatoid papulosis (bath PUVA) [18] Keratosis lichenoides chronica (bath PUVA) [19] Vitiligo (bath PUVA) [20] Urticaria pigmentosa/systemic mastocytosis [21] Generalized Schamberg's disease [22] Generalized granuloma annulare (bath PUVA) [23] Pansclerotic morphea (UVA) [24] Pansclerotic morphea [25,26] Cutaneous graft versus host disease (bath PUVA) [27] Palmoplantar keratoderma (bath PUVA) [28] Atopic dermatitis [29] BBUVB Psoriasis [16,30] Atopic dermatitis [16] Pityriasis lichenoides chronica [16] NBUVB Vitiligo [31,32] Psoriasis [33,34] Atopic dermatitis [33] Mycosis fungoides [35] Keratosis lichenoides chronica [36] Lichen nitidus [37] UVA1 (not discussed) Morphea, low-dose UVA1, combined with calcipotriol [38] Disabling pansclerotic morphea [39] Lichen sclerosus et atrophicus, low dose [40] Chronic graft versus host disease [41,42] Hypopigmented mycosis fungoides [43] been proven and, in comparison to BBUVB, it elicits faster clearance of lesions, fewer episodes of erythema and longer remission. However, large studies on phototherapy in childhood psoriasis are rare.…”