PWE-267 Urinary TLR4: a novel biomarker to identify patients with acute kidney injury in patients with acute on chronic liver failure: Abstract PWE-267 Figure 1

Abstract

animals. Correspondingly, metabolic profiles from both HCC groups with and without norfloxin were similar in character with the norfloxin treated group showing a slightly weaker set of metabolic alterations. Conclusion The spectral profiles of plasma in rats with HCC display marked changes with relation to lipid metabolism and cellular turnover which may indicate a fundamental repression of fatty acid oxidation and cancer cachexia. Norfloxacin appears to abrogate these effects slightly. This is the first animal model plasma 1 H NMR study to report such findings and may both be translational to human disease and allow the study of the effect metabolic modulation upon HCC progression.