Pyelonephritis lenta. Consideration of childhood urinary infection as the forerunner of renal insufficiency in later life.

MacGregor, Malcolm E.

doi:10.1136/adc.45.240.159

Cited by 42 publications

(9 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is evidence for a falling prevalence of this condition, which is probably due to a true reduction of reflux nephropathy because of modern medical care, particularly the treatment of acute pyelonephritis with antibiotics; alternatively the decline may represent changing fashions in disease classification. The historical aspects are discussed in detail by MacGregor17 who considered that VUR was crucial to the development of reflux nephropathy.…”

Section: Historical Perspectivementioning

confidence: 99%

Prognosis for vesicoureteric reflux

Jones

1999

Archives of Disease in Childhood

View full text Add to dashboard Cite

Section: Historical Perspectivementioning

confidence: 99%

Prognosis for vesicoureteric reflux

Jones

1999

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…The infecting organisms in the majority of the cases are Escher ichia coli bacteria belonging to a rather limited number of serological groups [1,12,15]. A large group of patients having a first attack of UTI attracts recurrences, often numerous, and in this group the risk for devel opment of renal parenchymal reduction and scarring seems appreciable [8,9], 1 Presented in part at the '3. Internationale Arbeitstagung über Probleme der Pyelonephritis', Bad Salzuflen, BRD, October 1970 [7).…”

mentioning

confidence: 99%

An Antigenic Relationship Between Kidney and Certa in <i>Escherichia col</i><i>i</i> Strains

Holmgren¹,

Hanson²,

Holm³

et al. 1971

Int Arch Allergy Immunol

View full text Add to dashboard Cite

By means of double diffusion analyses supplemented with absorption experiments an antigenic relationship was shown between human kidney and three out of nine tested E.coli strains. Antiserum to bacteria of these strains (serotypes O2:K1:H4, O14:K7:H- and O22:K13:H1) precipitated with kidney antigen from three adults and one infant, and antiserum to human kidney precipitated with veronal buffer extract antigens from the 3 E.coli strains. The veronal buffer extract antigen from the O2 strain contained at least 2 such antigenic factors, one related to the O2 lipopolysaccharide and another which was present also in the O22 and the O14 strains in an antigenically identical or related form. No antigens related to the tested E.coli strains were found in spleen, liver or AB Rh( + ) red cells. A possible significance of this antigenic relationship between kidney and some E.coli strains for the pathogenesis of the renal parenchymal reduction and scarring processes observed in some cases of pyelonephritis is proposed.

show abstract

“…Among the causes of papillary necrosis in humans are diabetes (Robbins & Angrist, 1949), pyelonephritis (Simon, Bennett & Emmett, 1957) and diabetic pyelonephritis (MacGregor, 1970).…”

Section: Discussionmentioning

confidence: 99%

Altered clinical and histological features of male MM mouse pyelonephritis associated with a change in its microbiology

1988

View full text Add to dashboard Cite

35Summary Radical changes in the clinical, microbiological and histological features of spontaneous pyelonephritis in MM male mice occurred when they were transferred to a new environment after Caesarian derivation. Although the incidence of pyelonephritis remained the same, the survival age was increased. The renal histology indicated a shift to a more chronic form of pyelonephritis with renal amyloidosis as a common feature. At autopsy much more renal scarring was seen, resulting in the 'shrunken' kidney typical of chronic pyelonephritis. Renal lymphocytic accumulations were commonly found in MM mice, but they were also seen frequently in C57BL mice and in germfree stocks of both strains: no association was found between these lesions and pyelonephritis.

show abstract

Pyelonephritis lenta. Consideration of childhood urinary infection as the forerunner of renal insufficiency in later life.

Cited by 42 publications

References 74 publications

Prognosis for vesicoureteric reflux

Prognosis for vesicoureteric reflux

An Antigenic Relationship Between Kidney and Certa in <i>Escherichia col</i><i>i</i> Strains

Altered clinical and histological features of male MM mouse pyelonephritis associated with a change in its microbiology

Contact Info

Product

Resources

About