Pyloric Atresia Type II

Bhatnagar, Sushmita

doi:10.47338/jns.v2.48

Cited by 2 publications

(2 citation statements)

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“…Patients with a gap atresia (type 3) are most often treated by gastroduodenostomy 4,8. As in our patient’s case, type 2 pyloric atresia is typically treated similarly to type 1 and may involve a Heineke-Mikulicz or Finney type pyloroplasty 4,8–10. While treatment of type 2 pyloric atresia has been primarily performed as part of a laparotomy,1,7,8,10 our case demonstrates the value of a laparoscopic-assisted approach which can allow for a smaller abdominal incision.…”

Section: Discussionmentioning

confidence: 55%

“…4,8 As in our patient's case, type 2 pyloric atresia is typically treated similarly to type 1 and may involve a Heineke-Mikulicz or Finney type pyloroplasty. 4,[8][9][10] While treatment of type 2 pyloric atresia has been primarily performed as part of a laparotomy, 1,7,8,10 our case demonstrates the value of a laparoscopic-assisted approach which can allow for a smaller abdominal incision. Ultimately, this approach allowed us to limit the incision size compared with a traditional laparotomy, which may have improved our patient's pain control.…”

Section: Discussionmentioning

confidence: 83%

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Laparoscopic-assisted Open Pyloroduodenostomy Repair of Pyloric Atresia in an Infant: A Rare Congenital Anomaly

Huerta

Sundin²,

Gilna³

et al. 2021

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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Purpose: Pyloric atresia is an uncommon congenital anomaly that may present with emesis and dehydration early in infancy. Definitive therapy consists of pyloroplasty or gastroduodenostomy depending on the subtype of atresia involved.Case Presentation: We report the case of a 2-day-old girl infant who presented with nonbilious emesis with feeds. Abdominal ultrasound and upper gastrointestinal series were performed and demonstrated a dilated, air-filled stomach with no distal air or passage of contrast. The patient was successfully treated by laparoscopic-assisted open pyloroduodenostomy of a type 2 pyloric atresia. Conclusion:Type 2 pyloric atresia is a rare clinical entity that can present with symptoms of gastric outlet obstruction. The patient described was treated by laparoscopic-assisted open pyloroduodenostomy, which has not been previously described for pyloric atresia. This work demonstrates an example of the safety and efficacy of laparoscopic surgery for infants with this anomaly.

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Section: Discussionmentioning

confidence: 55%

Section: Discussionmentioning

confidence: 83%

Laparoscopic-assisted Open Pyloroduodenostomy Repair of Pyloric Atresia in an Infant: A Rare Congenital Anomaly

Huerta

Sundin²,

Gilna³

et al. 2021

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

View full text Add to dashboard Cite

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Genome-wide association scan for QTL and their positional candidate genes associated with internal organ traits in chickens

et al. 2019

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Background Poultry breeding programs have been focused on improvement of growth and carcass traits, however, this has resulted in correlated changes in internal organ weights and increased incidence of metabolic disorders. These disorders can affect feed efficiency or even cause death. We used a high density SNP array (600 K, Affymetrix) to estimate genomic heritability, perform genome-wide association analysis, and identify genomic regions and positional candidate genes (PCGs) associated with internal organ traits in an F2 chicken population. We integrated knowledge of haplotype blocks, selection signature regions and sequencing data to refine the list of PCGs. Results Estimated genomic heritability for internal organ traits in chickens ranged from low (LUNGWT, 0.06) to high (GIZZWT, 0.45). A total of 20 unique 1 Mb windows identified on GGA1, 2, 4, 7, 12, 15, 18, 19, 21, 27 and 28 were significantly associated with intestine length, and weights or percentages of liver, gizzard or lungs. Within these windows, 14 PCGs were identified based on their biological functions: TNFSF11 , GTF2F2 , SPERT , KCTD4 , HTR2A , RB1 , PCDH7 , LCORL , LDB2 , NR4A2 , GPD2 , PTPN11 , ITGB4 and SLC6A4 . From those genes, two were located within haplotype blocks and three overlapped with selection signature regions. A total of 13,748 annotated sequence SNPs were in the 14 PCGs, including 156 SNPs in coding regions (124 synonymous, 26 non-synonymous, and 6 splice variants). Seven deleterious SNPs were identified in TNFSF11 , NR4A2 or ITGB4 genes. Conclusions The results from this study provide novel insights to understand the genetic architecture of internal organ traits in chickens. The QTL detection performed using a high density SNP array covered the whole genome allowing the discovery of novel QTL associated with organ traits. We identified PCGs within the QTL involved in biological processes that may regulate internal organ growth and development. Potential functional genetic variations were identified generating crucial information that, after validation, might be used in poultry breeding programs to reduce the occurrence of metabolic disorders. Electronic supplementary material The online version of this article (10.1186/s12864-019-6040-3) contains supplementary material, which is available to authorized users.

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Pyloric Atresia Type II

Abstract: Successful management of a neonate with type II pyloric atresia is reported and the relevant literature has been briefly reviewed.

Cited by 2 publications

References 12 publications

Laparoscopic-assisted Open Pyloroduodenostomy Repair of Pyloric Atresia in an Infant: A Rare Congenital Anomaly

Laparoscopic-assisted Open Pyloroduodenostomy Repair of Pyloric Atresia in an Infant: A Rare Congenital Anomaly

Genome-wide association scan for QTL and their positional candidate genes associated with internal organ traits in chickens

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