Pyloric Stenosis in Adults

Effects of gastric surgery upon gastric emptying in cases of peptic ulceration.

“…Gastric stasis has been named as the cause of post-vagotomy diarrhoea, either by causing gastritis and bacterial fermentation in the stomach (Dragstedt and Woodward, 1951) or by overstimulating the gastro-ileo-colic reflex, just as 20% patients with pyloric stenosis develop diarrhoea (Howe and Spence, 1960). In this series, post-vagotomy diarrhoea was rare, and was not associated invariably with a gross gastric stasis.…”

69-Year-Old Woman With Progressive Weakness and Anorexia

“…Acquired pyloric stenosis is uncommon and can be associated with malignancy, peptic or duodenal ulcer disease, bezoars, and intra-abdominal adhesions. [6][7][8][9] Historically, pyloric stenosis was most commonly attributed to excess gastric acid, but with the advent of proton pump inhibitors, malignancy should be strongly suspected in adult pyloric stenosis. Our patient had no history of peptic ulcer disease, gastroesophageal reflux, and biopsy specimens were negative for H. pylori.…”

NSAID-induced pyloric stenosis leading to oesophageal intramucosal dissection

“…Benign peptic ulcer disease is the most common cause of pyloric stenosis in adults 4. Her habitual ingestion of NSAIDs had resulted in peptic ulcer disease that led to a cicatricial narrowing of the pylorus.…”