Pyogenic brain abscess

Abstract

<jats:p>✓ Brain abscesses have been one of the most challenging lesions, both for surgeons and internists. From the beginning of the computed tomography (CT) era, the diagnosis and treatment of these entities have become easier and less invasive. The outcomes have become better with the improvement of diagnostic techniques, neurosurgery, and broad-spectrum antibiotics. Atypical bacterial abscesses are more often due to chemotherapy usage in oncology, long life expectancy in patients with human immunodeficiency virus (HIV) infection, and immunosuppression in conjunction with organ transplantation. Surgical treatment options showed no significant difference with respect to mortality levels, but lower morbidity rates were achieved with stereotactically guided aspiration. Decompression with stereotactically guided aspiration, antibiotic therapy based on results of pus culture, and repeated aspirations if indicated from results of periodic CT follow-up scans seem to be the most appropriate treatment modality for brain abscesses. Immunosuppression and comorbidities, initial neurological status, and intraventricular rupture were significant factors influencing the outcomes of patients. The pitfalls and evolution in the diagnosis and treatment of brain abscesses are discussed in this study.</jats:p>

A Case of Brain Abscess Due to Fusobacterium nucleatum Confused with Intracranial Tumor

“…BBA'nde anaerop bakteriyel etkenler tüm olguların neredeyse yarısından sorumludur (5) . Dental kaynaklı beyin apselerininde en sık rastlanan mikroorganizmalar Streptococcus viridans veya S. milleri ile F. nucleatum'dur (12) .…”

“…Anaerop bakteriyel etkenler tüm olguların %30-50'sini oluşturmaktadır (5) . Oral, gastrointestinal, ürogenital ve üst solunum yolu florasın-da yer alan gram negatif, anaerop basil olan Fusobacterium nucleatum; genellikle periodontite neden olmakla birlikte, oral hijyeni kötü olan hastalarda sıklıkla sekonder beyin apselerine de neden olabilmektedir (6)(7)(8)(9) .…”

Surgery for pyogenic brain abscess over 30 years: evaluation of the roles of aspiration and craniotomy

“…Pyogenic brain abscess (PBA) is an acute focal cerebral inflammation that is life-threatening if not treated properly (6,14). The condition is challenging to treat, especially in developing countries.…”

“…The choice of surgical procedure has been a subject of debate in recently published studies (1,6,7,11,17). The use of excision by craniotomy as a standard treatment has declined noticeably, and the preferred method is currently surgical aspiration (1,10,19).…”

“…The use of excision by craniotomy as a standard treatment has declined noticeably, and the preferred method is currently surgical aspiration (1,10,19). However, some authors concluded that craniotomy is the preferred surgical method for pBa (6,7,16,26).…”