Pyogenic brain abscess in Thailand

Wiwanitkit, Somsri; Wiwanitkit, Viroj

doi:10.4103/1947-2714.97200

Cited by 16 publications

(13 citation statements)

References 12 publications

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“…[4] Infection can spread from middle-ear to vital structures such as mastoid, facial nerve, labyrinth, lateral sinus, meninges and brain leading to mastoid abscess, facial nerve, paralysis, deafness, lateral sinus thrombosis, meningitis and intracranial abscess. [56] Of all the complications, hearing loss associated with chronic ear discharge is nearly always significant, reported in 50% of cases and tending to be more severe than those reported in other types of otitis media. [7] Complications associated with CSOM were frequent in pre-antibiotic era, however, the introduction of antibiotics gave clinicians a tool to be used even without the precise etiological diagnosis and the irrational use of antibiotics led to the emergence of multi-drug resistant bacterial strains and disease complication in return.…”

Section: Introductionmentioning

confidence: 99%

Microbiology of chronic suppurative otitis media in a tertiary care setup of Uttarakhand state, India

et al. 2013

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Background:Chronic suppurative otitis media (CSOM) is a notorious infection and a major health problem in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity ensures prompt clinical recovery and possible complications can thus be avoided.Aims:The aim of this study was to isolate the organisms associated with CSOM and to detect the antibiogram of the aerobic isolates.Materials and Methods:A total of 204 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and cultured for microbial flora. Drug susceptibility testing for aerobic isolates was conducted using Kirby-Bauer disc diffusion method.Results:The most common causative organisms isolated were Staphylococcus aureus (48.69%) and Pseudomonas aeruginosa (19.89%) amongst the 191 aerobic isolates. Anaerobes accounted for 29.41% of the isolates while 12.25% were fungi. Antimicrobial profile of aerobic isolates revealed maximum sensitivity to amikacin (95.5%), ceftriaxone (83.4%) and gentamicin (82.7%).Conclusion:Knowing the etiological agents of CSOM and their antimicrobial susceptibility is of essential importance for an efficient treatment, prevention of both complications and development of antibiotic resistance and finally, the reduction of the treatment costs.

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Section: Introductionmentioning

confidence: 99%

Microbiology of chronic suppurative otitis media in a tertiary care setup of Uttarakhand state, India

et al. 2013

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“…[3] [5] Infection can spread from middle-ear to vital structures such as mastoid, facial nerve, labyrinth, lateral sinus, meninges and brain leading to mastoid abscess, facial nerve, paralysis, deafness, lateral sinus thrombosis, meningitis and intracranial abscess. [6,7] Of all the complications, hearing loss associated with chronic ear discharge is nearly always significant, reported in 50% of cases and tending to be more severe than those reported in other types of otitis media. [8] Complications associated with CSOM were frequent in pre-antibiotic era, however, the introduction of antibiotics gave clinicians a tool to be used even without the precise etiological diagnosis and the irrational use of antibiotics led to the emergence of multi-drug resistant bacterial strains and disease complication in return.…”

Section: Introductionmentioning

confidence: 99%

An observational study of Microbial profile of patients with Chronic Suppurative Otitis Media (CSOM): A hospital based study

Sarfaraz¹

2017

jmscr

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“…8,9 An ear infection is caused by a bacteria or virus in the middle ear. 10 Mainly ear pain, fullness in ear, hearing loss, ringing in the ears, discharge, nausea, vomiting and vertigo are the symptoms of ear infections. 11 Some others ear diseases are otitis media with effusion and fluid buildup in the middle ear and chronic suppurative otitis media, a persistent ear infection resulting in tearing or perforation of the eardrum.…”

Section: Introductionmentioning

confidence: 99%

“…11 Some others ear diseases are otitis media with effusion and fluid buildup in the middle ear and chronic suppurative otitis media, a persistent ear infection resulting in tearing or perforation of the eardrum. 10 Sinus infection is the mostly common disease of nose. Teeny holes that connect nasal passage to sinuses get blocked and causing growth of microorganisms leads to sinus infection.…”

Section: Introductionmentioning

confidence: 99%

A survey of prescription pattern of antibiotic drugs on patients suffering from ENT infection within Dhaka metropolis

Karim

Uddin

Rahman

et al. 2017

Int J Basic Clin Pharmacol

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Background: This survey was designed to assess and evaluate the prescription pattern of antibiotic drugs on patients suffering from ENT infection within Dhaka metropolis.Methods: A cross sectional, observational and prospective study was conducted from January to June 2015 in the out-patients (OPD) and in-patients (IPD) of ENT department at different general and specialized government and private hospitals (Dhaka Medical College and Hospital, Sir Solimullah Medical College Mitford Hospital, Holy Family Red Crescent Medical College and Hospital, Dhaka Community Medical College and Hospital) within Dhaka city.300 prescriptions were collected and randomly evaluated for this present study.Results: Out of 300 patients, 220 (73.33%) were male and 80 (26.67%) were female (including children and adults) where most of the patients were outpatients 262 (87.33%). In the patients information section it was observed that approximately 93.33% prescription contained antibiotic drugs and almost all prescription (100%) contained antibiotic drugs along with other drugs such as 80.67%PPI (proton pump inhibitors), 76.67% analgesic and 51.33% vitamin / iron supplements. From this analysis we found that 19.33% prescription contained single antibiotic drug, 80.67% contained two antibiotic drugs and no prescription contained more than two antibiotic drugs. Most of the prescribed drugs were administered orally (12% capsule, 80% tablet form). Out of 473 prescribed antibiotic drugs majority of them lie underβ-Lactam (54%) class followed by cephalosporin (46.33%) class in which maximum drugs (92%) were prescribed by their brand names.Conclusions: Prescribing more than one antibiotics was commonly encountered in this study indicating the occurrence of polypharmacy. Interventions to rectify over prescription of antibiotics, use of brand names, inadequate labelling of drugs is necessary to improve rational drug use. Standard treatment guidelines, hospital formulary, and educational intervention become essential to modify this behaviour to benefit the patient.

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Pyogenic brain abscess in Thailand

Cited by 16 publications

References 12 publications

Microbiology of chronic suppurative otitis media in a tertiary care setup of Uttarakhand state, India

Microbiology of chronic suppurative otitis media in a tertiary care setup of Uttarakhand state, India

An observational study of Microbial profile of patients with Chronic Suppurative Otitis Media (CSOM): A hospital based study

A survey of prescription pattern of antibiotic drugs on patients suffering from ENT infection within Dhaka metropolis

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